In this article, three stages of rising, flourishing and falling of deism are studied and reviewed. First, deism, reason and revelation are considered to pave the way to the essential truth and can both separately guide us close to God and the immortality of soul.Influenced by the progress of science, deism, at second stage, leads man astray from the Worshiped God of all religions to a God which is figured as a cosmic engineer. This God is the very God of gaps, not the creator and the teacher. The third stage is -the era of the absence of that cosmic engineer or God of gaps. This God has forsaken this gigantic cosmic machine, and neither has a presence in the history of human being nor satisfies our needs.Deism declined and ended up dead for three reasons :1) Inner weakness of argument from design; the only argument adopted by deist. 2) The abstract nature of its concepts. 3) The dominance of the church and its opposition to revelation.Thomas Hobbes, Henry More, Robert Boyle and Isaac Newton had a strong influence on deism. They had been influenced by Descartes, had criticized him and shared his ideas as well. Their understanding of the nature of science and its methodology had obviously a profound impact on their followers and later philosophers. Another purpose of this article is to analyze the discussions put forward from the view of these four thinkers and to study their ideas about God.