Various Forces such as those arising from weight, earthquake, wind, waves, hydrostatic and hydrodynamic forces affect the structure of Radial Gate. The calculation and analysis of Radial Gate affected by each of these forces are important matters, which are of special importance in relation to the strength and durability of the gate structure.In this paper, as a case study, effort has been made to optimize the specifications of Karkheh dam’s Radial Gate against forces applied to it.The purpose of optimization analysis is minimize or maximize the goal functions for stiffness, natural frequency, structural energy, etc to find the best shape for radial gate. In this method, the optimized parameter is material distribution.The finite element model developed with goal functions and constraints and so the problem is solved.In this research, the first order method algorithm is used. The dimensions of Karkheh dam radial gate are optimized with optimization module of ANSYS 10.0 software. The reduction of structure weight (about 1.8 percent) is optimized in seventh record. The best safety factor is obtained in this record and the value of it is 6.45.