Jentashapir Journal of Cellular and Molecular Biology
Year:2013 | Volume:4 | Issue:1|Papers Count:10

Background: Using chemical drugs have often masses of damaged side effects Therefore, it is important to research about medicinal plants with anti-inflammation and fewer side effects. malvasylvestris has potential use as a medicinal plant. The aim of this study was to investigate the effect of Malva Sylvestris flowers hydroalcoholic extract on the carrageenan-induced inflammatory response using Wistar male rats' paws. Methods: Malva Sylvestris flowers powder was macerated with 70%ethanol, and its extract prepared. Male Wistar rats were divided into 6 groups of 10 animals each for following treatments: Malva extract (200, 400, 600 and 800 mg/kg), normal saline (5mg/kg) as negative control and Aspirin (300mg/kg) as a positive via IP. Thirty min later inflammation was induced by injection of 100μlcarrageenan (1%W/V) into the rat's hind paw of rats (SC). The inflamation response changes were inspected over 5 hours every hour, using plethysmometer.Results: The extract-treated (600, 800 mg/kg) showed considerable reduction in the rats' paws inflamation when compared with control groop (p>0.05). But 200 and 400 mg/kg extract showed no considerable decrease in inflammation when comparied with control group (p<0.05). There was not significant differences between doses of 600 and 800 mg/kg of extract, therefore dose of 600 mg/kg was selected as the most favorable dose as anti-inflammation.Conclusion: These findings demonstrate that extract of M. sylvestis could accelerate reducing inflammation responses in rats and supports its traditional and probably medicinal benefits use.

Background: One of the main objects in medical science is diagnosis the diseases and classification the patients to different classes. Consequently according to the above the patients that set in one classes should have maximum similarity with each other. Discrimination and classification analysis have been frequently used in medical data for diagnosis and prognostic of the disease. The wrong in the medical diagnosis is very important, hence the decrease of wrong diagnosis in the discrimination methods are to consider always. Different methods have been used for classification and discrimination of medical data for years. The intention of this research is determination the state of tiroid gland using linear, quadratic and logistic discrimination in camper with the most up-to-date method neural network discrimination.Methods: A total of 225 patients’ data from Jahad university laboratory has analyzed. The obtained data correlated to November 2005. Using spluss/2000 software the collected information proceeds within four methods.Results: The consequences revealed that linear discrimination misdiagnosis with training set and test set were 0.14 and 0.213 respectively. However these figures considered by quadratic discrimination were 0.053 and 0.106 correspondingly. The obtained records through logistic discrimination for both training set and test set was 0.026 and 0.026. Yet these facts for neural network discrimination recorded in 0.02 and 0.013 likewise.Conclusion: The neural network discrimination had possibly superior decrease in wrong diagnosis and with notice to the fact that the method need a very fewer statistical assumption, this method is proposed.

Background: Nowadays, it is essential to appreciate the mental health status of all people specially students because they experience different kinds of emotional stress. Mental health status of students who work in different sections of the hospital, like operation rooms is affected by stressful factors. The aim of the investigation was to study the mental health within the operation rooms students from Nursing and Midwifery Schools to discover vulnerable students. Methods: A descriptive-analytic study developed on the students of the Ahvaz Nursing and Midwifery Schools (n=139) using the census method. In this observational descriptive analytic study, The demographic data and pattern of mental health were collected by standard general health questionnaire (GHQ-28). Data was analyzed using statistical software SPSS (version17), t test and variance analysis with 95% coefficient interval were used.Results: Based on data analysis results12.5% of the students suspected to have mental health, 62.5% were in good mental health shape and 25% of them were vulnerable. Based on t test and variance analysis, it has been revealed that there is statistically a significant relationship between the mental health and the number of family members (p<0.05), In addittion, there is no significant difference between the mental health status and demographic factors such as sex, dormitory and non-dormitory, single and married students.Conclusion: Having noticed that a significant percentage of students facing with not being well in view of the fact of mental health status therefore, encouraging them refer to mental health services centers receiving appropriate consultant advices could help improving their mental health status.

Background: patients can develop complications and prevent unwanted side effects and additional costs on patients and hospitals by knowing methods of anesthesia. The purpose of this study is evaluating patients' awareness for elective surgery on spinal and general anesthesia and factors influencing their preference.Methods: In study a cross-sectional method was developed to evaluate 273 elective surgery patients who admitted to Imam Reza educational hospital and Al-Zahra hospital in Tabriz over 90-91. A questionnaire was composed of two parts and data were collected over 90-91: Data were analyzed by SPSS software and a descriptive statistics method was applied to process the data using t -test.Results: The spinal anesthesia method was the first choice of 63 patients due to wakefulness, alertness and other patients' experience perception during the surgery operation. From this group 20.63 % did not have any preference for either methods.However, fear of surgery, panicking of being witness through the surgical procedure and not being vigilant in operation room during surgery were reasons for patients to go for general anesthesia method and 22.98% had no any specified reason for their choice. The t- test did find a significant correlation among level of awareness and understanding of methods of anesthesia, gender, occupation and education.Conclusion: The majority of patients have a little knowledge about anesthesia methods. Therefore, improving patients' awareness needs serious efforts of media and health centers, especially hospitals, doctors and the national anesthesia association. Unwell-educated patients need also more efforts improving their knowledge regarding anesthesia techniques.

Background: Patients with breast cancer often have to deal with severe drug side effects and psychological distress during cancer diagnose and cancer treatment. Anxiety is the psychiatric problems encountered in breast cancer patients. alongside medical treatment, many breast cancer patients use forms of Complementary and Alternative Medicine (CAM) to manage the above side effects. This study aimed to determine the effect of yoga program on anxiety in breast cancer patients undergoing chemotherapy referred to Radiotherapy and Oncology Center of Golestan Hospital in Ahwaz.Methods: A clinical trial plan study was designed and a total number of 60 breast cancer patients were selected. The patients were randomly divided in to two group Yoga (n=30) and control (n=30). In the yoga group the intervention conducted 30 min yoga prior to their primary chemotherapy, the subjects were asked to practice daily as homework. While the control group was instructed encouraging therapy during their hospital visits as a part of regular care. Data were collected and assessed with Speilberger's State and Trait Anxiety Inventory.Results: The final results showed overall decrease in both self reported state and trait anxiety and total score anxiety in yoga group as compared to controls group (P<0.05).The study revealed that there is a positive correlation between anxiety states and traits with symptom severity and distress during conventional treatment intervals.Conclusion: The results suggest that yoga intervention as a nonpharmacological method can be used for managing anxiety in breast cancer patients.

Background: Service Quality generally refers to the non-health and non-clinical aspects of the health services and mainly focuses on relationship between care provider and health customers, and the environment in which care services are delivered. Because of undeniable role of service quality on the improving health results, this study aims to assess Service Quality in Rehabilitation Faculty physiotherapy clinic of Tabriz University of Medical Sciences.Methods: This cross-sectional study conducted with 204 participants (patients and coadjutors) using a valid and reliable questionnaire in physiotherapy clinic. Service Quality was assessed by the following formula {SQ=10- (Importance×Performance)} based on two main dimensions of Importance and Performance. Importance scores ranged from 1 to 10 and performance score varied from 0 to 1.Results: Study finding showed that from the participants’ perspective choice of care provider, safety and prevention and early detection achieved the lowest service quality score and aspects of timeliness, confidentiality and quality of basic amenities had the highest service quality score respectively.Conclusion: For six aspects of service quality including choice of care provider, autonomy, dignity, safety, prevention and early detection and availability and access quality score was lower than acceptable score (9) and indicating good opportunity to improve quality of delivered care.

Background: Ethical climate is an important component of organizational culture. Nurses’ perception of hospital ethical climate can influence their performance and attitudes related to ethical issues. This investigation explores a survey of nurses in different cultural settings to divulge their perceptions of ethical position responsibilities applicable to nursing practice.Methods: A descriptive design was applied in this study. A total number of 125 nurses from 5th Azar Hospital were contributed in this study. The reliability and validity of the measures were assessed using a demographical questionnaire along with Hospital Ethical Climate Questionnaire (HECQ).Collected data analyzed through statiscal descriptive using Statistical Package for Social Science (SPSS), Version 16.Result: Multidimensional preference analysis discovered the patterns of mean rankings given by the nurses to the questionnaires they considered as important ethical climate as followed: patient (2.773), manager (3.798), hospital (3.115), and physician (2.799).conclusion: The findings indicate that the ethical climate outlined by nurses could embedded sociocultural factors that influence nurses' perceptions in the realities of nursing performance. The nurses ranked hospital ethical climate from moderate to highly developed. Ethical climate is an important factor in job performance and also affect on quality of patient care. Therefore, this study suggests that hospital leaders should apply strategy to promote hospital ethical climate manager of hospitals can also promote nurses’ performance by creating environment which supported nurses.

Background: Breast cancer is the most common cancer in women and breast self-examination Due to simplicity, economical and efficiency is vital factor in Escalating the treatment and survival of Women involved with breast cancer. The purpose of this study was to investigate the knowledge, attitude and practice on breast self examination among the female students of Ahvaz Jundishapur University of Medical Sciences.Methods: A cross-sectional descriptive questionnaire study was conducted on 237 female students with at least 20 years old. The group sample was selected through stratified random method from Student dormitories’ of Ahvaz Jundishapur University of Medical Science. Data were analyzed using SPSS software (version 19). Descriptive statistics added chi-square test were used for analysis of categorical variables obtaining the consent and assuring the respondents of confidentiality of responses the investigating was developed.Results: The aimed groups of female students with average of 23.33±3.14 had good (14.9%), moderate (42.2%) and poor awareness (13.9%) respectively. The maximum score with 93.3% as positive and the minimum of 6.8% as negative attitude for sample grouped students were recorded for this study. Scores upon correlation revealed a significant correlation between knowledge and attitude (P<0.001). For the practice score, 52.7% of students had carried out self-examination. There was also a statistically significant relationship between practice and knowledge (P<0.001), Married couples practiced significantly better self examination than single ones (P<0.01).Conclusion: Results showed that despite their profession in the future, medical students had insufficient knowledge on breast self examination. The study highlights the necessitate for educational courses to create awareness on the subject of habitual breast cancer screening behavior and effective training sessions are required in collaboration with the Nursing-Midwifery and Medicine faculties.

Survival and growth of today's organizations require ability of responding timely and appropriately against such fluctuations.The organizations that can timely forecast their needs and environmental changes should focus and emphasis on organizational learning. The present study aims to revalidate a measurement scale for organizational learning capability in the context of faculty members of Ahvaz Jundishapur University of Medical Sciences in 2011.The statistical population Consists 506 of all employed faculty members in the Ahvaz Jundishapur University of Medical Sciences. Of which 165cases were selected as targeted sample using the Cochran formula by Stratified random sampling method. Finally, data was collected by questionnaire and analyzed by descriptive statistics and ANOVA Test Using confirmatory factor analysis, the construct measurement model was tested and the scale was corroborated.The results showed that among the components of organizational learning, management commitment was the highest average (14.66) and then, knowledge transfer and integration component (13.48) and finally, opening & experimentation was the lowest (11.93).In conclusion, components of organizational learning among the faculty members are in poor condition that needs to be reinforcement. Therefore, improving the knowledge base of the organization through supporting organizational learning is necessary by reflection, evaluation, and constant feedback in every organization's aspects.