Objective(s): This study aimed to perform a review of the literature to examine sexual behavior in Iran.Methods: A review of Iranian literature covering all full publications in both Persian (2001- 2015) and English language (2010-2015) on sexual behavior was carried out. The search strategy included a combination of keywords ' 'Jensi' [Sexuality], Jema' [Coitus], Nazdiki [Coition], 'Mogharebat' and ' sexual attitude', 'sexual practice', "sexual performance', 'sexual function', 'sexual dysfunction', ’sexual satisfaction', 'sexual behavior in English language. All papers were filtered by 'Hamkhabegi/Hambastari' [Intercourse], in Persian language and ' Sexual', Sexual knowledge', keywords in title, abstract and keywords. The databases we used to search the publication in Persian language were Iran Medex, Magiran and SID.Furthermore, in English language PubMed/Medline, Scopus, Science Direct and ProQuest were used. A total of 1182 abstracts were identified and after exclusion of 234 duplicates and irrelevant papers, 951 abstracts were reviewed by 2 investigators.Results: All scientific documents were categorized in three bio-medical, psychological and sociological domains. According to the data pool, 481 articles were classified in bio-medical, 347 in psychological and 123 articles in sociological domain.Conclusion: There was relatively acceptable evidence on bio-medical and psychological issues. However, providing enough evidence on sociological perspective need further well designed investigations.