The study of higher education policies of developed countries in the design and development of university entrepreneurship ecosystem has become one of the new and important research topics in the field of higher education and university entrepreneurship ecosystem. Therefore, changing the approach of universities from educational and research planning to approach Creating a university entrepreneurial ecosystem has attracted the attention of the world’ s leading universities. Due to the lack of experience in the agricultural sector, the ecosystems of the fledgling agricultural business system should be identified using the teachings of pioneering entrepreneurship departments. The aim of this study was to evaluate the ecological model of university entrepreneurship system based on Eisenberg model and with emphasis on higher education in the country from the perspective of experts in start-ups, which was practical in terms of purpose and was implemented using a questionnaire. The statistical population of the study included 1550 graduate students from five universities of Ilam, Kurdistan, Razi, Lorestan and Bouali Sina universities, using the Bartlett table, 315 of them were performed by cluster method with appropriate proportion and sampling. To measure the validity of the research instrument, a diagnostic validity method was used, the value of which was higher than AVE≥ 0. 5 for acceptable structures. In order to determine the reliability, a composite reliability method was used, the value of which was higher than CR≥ 0. 6 for the studied structures and was acceptable. The value of the sequential theta coefficient was also calculated for structures higher than θ ≥ 0. 7 In order to process the data, exploratory factor analysis and confirmatory factor analysis were used. Then, the measurement model showed that the conceptual modeling factors of academic entrepreneurship climate in agricultural colleges in western Iran, including supportive factors of support, economic, political, political, socio-cultural governance, interactions, networking and human capital, play the greatest role in forming an academic entrepreneurial ecosystem. They have in agricultural colleges.