Purpose: To evaluate influencing factors on decision to reclassify resources in libraries of Tehran, Iran and Shahid Beheshti universalities of medical sciences.Methodology: Using desk research, the determining factors for decision on reclassification were obtained and then library managers were surveyed using a selfdesigned questionnaire.Results: “Executive facilities” and “perceptual factors (realizing the necessity to change), are the most determining factors to convince library managers for reclassification. Also, there are other influencing factors such as budget and continuance of library services, manager support, library collection integrity, unproper current classification and automating the change process. The less influencing factors on managers’ decisions are providing enough information and data to set purposive and proper plan for reclassification, better browsing in new classification system and ease of user training and adaptation.Conclusion: Medical Libraries should employ a realistic view to evaluate factors influencing reclassification. There is no single predetermined model to prove reclassification will cause remarkable improvement.