The purpose of the present study was to determine the relationship between maximum aerobic power and coronary heart disease risk factors. Fifty nine male subjects (age=21.15±2.55 yr, height=174±6.83 cm, weight=70.26±12.62 kg) were selected randomly from Khoramabad Azad University. Subjects took the 1.5-mile test. We measured weight, height, abdominal circumference, hip circumference and also skin fold in chest, abdomen, thigh to determine %BF. Finally, we determined coronary heart disease risk factors such as TC, LDL-C, HDL-C, TG, TC/HDL and WHR. To analyze data, Pearson correlation coefficient was used and minimal level of significance was (P<0.05). The results showed that there was a reverse significant relationship between maximum aerobic power and TG, LDL-C, WHR, FFM, BF% and BMI (P<0.01) and TC (P<0.05) whereas there is not a significant relationship between maximum aerobic power and HDL-C and TC/HDL. The results showed that physical activity can influence body composition and satisfactory effect on serum lipids. An increase in physical activity level causes a decrease in CHD risk factors.