The Central Zagros is a natural corridor connecting eastern and western parts of the Parthian lands. It has been also considered as King Road through the Achamenids and known as Silk Road during the Parthians and Sassanians. The geographical characteristics of the area have been favorable to inhabit by various groups of people traced back to the early Neolithic period.Archaeological survey has been conducted in the study area, and approximately 340 Parthian (ca. 250 B.C.-225 A.D.) archaeological sites have been discovered and recorded. The goal of this project is to develop a set of simple processes that can be widely used to build basic models of site locations and settlement patterns. Two main issues were concerned in this paper, (I) technical aspects regarding basic methods for data acquiring, and GIS based processing and analysis, (2) modeling archaeological site distribution patterns related to the available archaeological and environmental data. In order to explore further the location of archaeological sites, a Geographical Information System (GIS) was developed combining all existing information produced from the recent survey of the area. The combination of this information into a GIS has resulted in a digital archive of the surveyed area that allows the user to simultaneously visualize and analyze all data within their original spatial contexts allowing a more comprehensive investigation of the sites. This digital database has been developed to synthesize information on site type, site size, site dating and site functions, which are used to address the issues regarding the changing settlement patterns in the study area. We found that settlement patterns arc, to a large extent, directly shaped by widely held cultural needs, they offer a strategic point for the functional interpretation of Parthian archaeological culture.