The studied region is located between 50 o 3´ to 52 o 6´ of the East and 34 o 8´ to 35 o 11´ of the North. This region was distinguished from Tehran province in 1375 and made Ghom province. Lets area is about 11238 square kilometers, i. e. about 0.68 percent of the country area. Ghom area is 116 square kilometers .Nowadays human bioclimatic studies and surveys are the base of urban planning’s, development, settlements, architecture, tourism and etc .This type of research can be used in human settlements on new regions .In this paper human comfort has been evaluated based on bioclimatic indexes and models of Becker,Terjung, stress pressure, Chill-wind and Term hygrometric using Ghom synoptic climatology station data during 1985 – 2005. Therefore, considering climatic characteristics of the studied region, the above mentioned methods may be used as a suitable guideline in exploiting environmental conditions. Considering different methods and indices, as well as the results derived from data analysis and also tables and diagrams taken from synoptic station of the studied area, we can acknowledge that a single index is not enough to get the best result. Therefore in order to reach the desired results, a combination of different indices is necessary. Terjung index, considering the studied region’s characteristics, have appropriate features especially for determining comfort conditions in warm regions. Becker index have approximately the same results. According to the available evaluations. Nervous pressure method and term hygrometric and Chill-wind methods are suitable and rank in the next positions. The results of this study shows that the bioclimatic condition of the region ranges from very hot to very cool throughout the year. Using these models and indicators, necessary evaluations and guidelines, regarding comfort and discomfort of human being in different occasions of the year are presented here which can be suitable for climatic conditions of Ghom. The result of this research may be the base of construction planning in this city.