Background and Objective: In verses of the Quran, Quran as spirthual healing has introduced. The history of Quran therapy dates back to the time of revelation. This dose not mean that the Quran only serves the healing of the souls and hearts, and frees the disease, but according to the validity of the verse, it can be said that the Quran is the healing of the body and the vhuman soul. With the Quran, physical and physical pain can be cured. As with the Quran, treated psychological and psychological pains, and those who suffered from illness, and health, in recent decades, several studies have been carried out on various aspects of the effect of Quran treatment on various mental, psychological and physical aspects of mankind.The aim of this study was to investigate and analyze the studies done regarding the effect of Quranic verses on the treatment of various diseaes and and the compilation of their results.Methods: This study was a kind of review that was carred out searched on sites google, google scholar, SID, Iranmedex, pubmed with key words the Quran, treatment physical diseaes, mental diseaes, on the treatment of physical and mental diseaes.Findings: The results of the studies show the effect of Quran on memory enhancement, increased mental health, aggression, anxiety and depression, treatment of mental diorders and sleep, improving vital signs, reducing pain, increasing optimism and life expectancy, helping patients to be more and more relaxed in dealing with problems by changing the pattern of brian waves and variouse therapeutic effects.Conclusion: There are plenty of narratives regarding the treatent of diseases with the Quran. Due to many traditions and practical experience, treatment with the Quran is definite. Howere, more research is needed to clarify the various dimensions.