Nowadays, science and technology have vital role in the growth and development of countries. The purpose of this study is presenting a process model of service commercialization in the chosen companies. Accordingly, we used case study methodology. First, by using non-random convenience sampling method, three companies, providing knowledge based services in the ICT industry in Qom and Tehran province, were selected. The data were collected conducting a deep interview with seven managers of this industry. Then, by using thematic analysis, the data were analyzed and the results were extracted. Finally, the process model of services commercialization in the knowledge-based companies in ICT industry was presented. The main steps of the model are marketing research (needs analysis), idea screening, analyzing and financing, providing and training human resources, designing and implementing marketing and advertising strategies, comprehensive production feasibility, production & testing & improvement & upgrading, quality control, obtaining licenses and standards, designing and implementing pricing & sales & distribution strategies.