This research was conducted to identify isozymes and starch accumulation in above graft union to anticipate the graft compatibility between pear cultivars and 'Quince A' rootstock. Seventeen pear cultivars ('Natanz', 'Shakari', 'Shah Miveye Esfahan', 'Tabrizi', 'Khoje Asiyabrak', 'Domkaj', 'Dargazi', 'Torsh', 'Bore Hardy', 'Aloret', 'Flestini', 'Lizbon', 'Bolghare No.2', 'Spadana', 'Koshiya' and 'Passcrasan') obtained from Karaj Seedling and Seed Center (KSSC) and Razavi Astaneh Ghods Gardens (RAGG). For electerophoresis experiments, bark and cambial tissues of rootstock and scion and for determination of amount of starch, bark and wood of rootstock and scion were used. Many isozymes band observed in rootstock and scions, but in present study this band was observed on band A (Rf= 0.86) which was in 'Bore Hardy' cultivar (compatible with 'Quince A'). The presence of this band in each scion showed incompatibility ('Shah Miveye Esfahan', 'Dargazi' and 'Torch'). There was another band (B, Rf= 0.68) in 'Bore Hardy' which was not found in 'Quince A'. The presence of B band in pear cultivars could indicate their compatibility with 'Quince A' ('Shakari', 'Lizbon', 'Bolgare No. 2', 'Khoje Asiyabrak', 'Domkaj', 'Koshiya'). Data analysis of starch accumulation showed that 'Natanz', 'Dargazi', 'Shah Miveye Esffahan', 'Aloret' and 'Torsh' cultivars accumulate starch in above graft union, while the rest cultivars did not show starch accumulation. In general, it can be concluded that 'Dargazi', 'Shah Miveye Esfahan', 'Aloret' and 'Torsh' cultivars are incompatible with 'Quince A', while 'Bore Hardy' and 'Passcrasan' cultivars are compatible.