THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT

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FARAMARZI AZITA; SEIFI BEHJAT; SOHANI MAHSA; SADEGHIPOUR RODSARI HAMID REZA

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Journal: Razi Journal of Medical Sciences Year:2011 | Volume:18 | Issue:91 Page(s): 1-6

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Title

THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT

Author(s)

FARAMARZI AZITA | SEIFI BEHJAT | SOHANI MAHSA | SADEGHIPOUR RODSARI HAMID REZA | Issue Writer Certificate

Keywords

VASECTOMYQ3

PROOXIDANT-ANTIOXIDANT BALANCEQ2

MALONDIALDEHYDEQ2

RATQ2

Abstract

Background: VASECTOMY is a widespread contraceptive method in men. In recent years, the number of men who perform VASECTOMY reversal is increasing. VASECTOMY has complications, probably leading to VASECTOMY reversal failure. It is assumed that oxidative stress is the main cause of these complications. The aim of this study was to investigate the indices of oxidative stress serum after VASECTOMY.Methods: In this experimental study, 42 male RATs were divided in 6 groups of seven each: bilateral VASECTOMY (15, 45 and 90 days) and sham (15, 45 and 90 days) groups. Serum PAB (Prooxidant- Antioxidant Balance) and MDA (Malondialdehyde) as a product of lipid peroxidation were measured 15, 45 and 90 days after intervention. Comparisons between groups were made by Repeated Measure test.Results: Our result showed that serum MDA increase after 15 days was not significant (2.95±0.12) in comparison to related sham group, but after 45 (3.6±0.12) and 90 (3.9±0.31) days the increase, compared to related sham groups 45 (2.28±0.28) and 90 (2.29±0.25)days, and also 15 days VASECTOMY group (2.95±0.12) were significant (p<0.001), and there was no significant increase in serum PAB at any times (p>0.05).Conclusion: Bilateral VASECTOMY increased serum levels of MDA. It is supposed that increase in MDA causes adverse effects and unsuccessful reversal VASECTOMY. By prescribing antioxidants, these effects can be decreased.

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APA: Copy

FARAMARZI, AZITA, SEIFI, BEHJAT, SOHANI, MAHSA, & SADEGHIPOUR RODSARI, HAMID REZA. (2011). THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 18(91), 1-6. SID. https://sid.ir/paper/10438/en

Vancouver: Copy

FARAMARZI AZITA, SEIFI BEHJAT, SOHANI MAHSA, SADEGHIPOUR RODSARI HAMID REZA. THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2011;18(91):1-6. Available from: https://sid.ir/paper/10438/en

IEEE: Copy

AZITA FARAMARZI, BEHJAT SEIFI, MAHSA SOHANI, and HAMID REZA SADEGHIPOUR RODSARI, “THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 18, no. 91, pp. 1–6, 2011, [Online]. Available: https://sid.ir/paper/10438/en

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