THE EFFECT OF AERIAL PARTS OF CONCURRENT HYDROALCOHOLIC EXTRACTS OF HYPERICUM PERFORATUM L. AND AMARANTHUS CAUDATUS L. ON FATTY STREAK FORMATION IN HYPERCHOLESTEROLEMIC RABBITS IN COMPARISON WITH LOVASTATIN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KABIRI NAJMEH; ASGARY SEDIGHEH; MADANI HOSSEIN; MAHZOUNI P.; RAHIMI PARIVASH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2009 | Volume:25 | Issue:1 (43) Page(s): 29-38

Download Full-Text

Persian Verion

View:

1,005

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF AERIAL PARTS OF CONCURRENT HYDROALCOHOLIC EXTRACTS OF HYPERICUM PERFORATUM L. AND AMARANTHUS CAUDATUS L. ON FATTY STREAK FORMATION IN HYPERCHOLESTEROLEMIC RABBITS IN COMPARISON WITH LOVASTATIN

Author(s)

Keywords

ATHEROSCLEROSISQ3

HYPERICUM PERFORATUM L.Q3

AMARANTHUS CAUDATUS L.Q3

RABBITQ3

LOVASTATINQ3

Abstract

Hypercholesterolemia and oxidative stress increase serum total cholesterol and LDL-C cholesterol levels resulting in increased risk for development of ATHEROSCLEROSIS. Antioxidants play an important role in inhibiting and scavenging radicals thus could be other important measures to benefit individuals with the increased cardiovascular disease risk factors. This study was designed to investigate the effect of aerial parts of HYPERICUM PERFORATUM L. and AMARANTHUS CAUDATUS L. on the development of ATHEROSCLEROSIS in male hyperlipidemic RABBITs. Twenty adult male RABBITs were randomly divided into four groups of five and were fed for 60 days as follows: basic diet, high cholesterol, high cholesterol along with combination Hypericum perforatum and Amaranthus caudatus (HA) extract (75mg/kg) and high cholesterol along with LOVASTATIN (10mg/kg). Blood samples were taken at the beginning, one month later and at the end of the study in order to measure their serum factors (cholesterol, LDL-C-C, HDL-C-C, TG). The fatty streak formation evaluated at the end of the study. The results showed that both the extract and LOVASTATIN reduced significantly the levels of cholesterol, LDL-C-C, triglyceride and HDL-C-C) increased in comparison with high cholesterol group. Fatty streak formation in extract recipient group significantly decreased in comparison with high cholesterol group with LOVASTATIN. The result showed that HA significantly decreased TG, cholesterol and fatty streak formation in comparison with high cholesterol group and LOVASTATIN. These findings suggest HA extract is more effective in decreasing the level of cardiovascular risk factors than LOVASTATIN in hypercholesterolemic RABBITs.

Cites

No record.

References

Cite

APA: Copy

KABIRI, NAJMEH, ASGARY, SEDIGHEH, MADANI, HOSSEIN, MAHZOUNI, P., & RAHIMI, PARIVASH. (2009). THE EFFECT OF AERIAL PARTS OF CONCURRENT HYDROALCOHOLIC EXTRACTS OF HYPERICUM PERFORATUM L. AND AMARANTHUS CAUDATUS L. ON FATTY STREAK FORMATION IN HYPERCHOLESTEROLEMIC RABBITS IN COMPARISON WITH LOVASTATIN. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, 25(1 (43)), 29-38. SID. https://sid.ir/paper/104699/en

Vancouver: Copy

KABIRI NAJMEH, ASGARY SEDIGHEH, MADANI HOSSEIN, MAHZOUNI P., RAHIMI PARIVASH. THE EFFECT OF AERIAL PARTS OF CONCURRENT HYDROALCOHOLIC EXTRACTS OF HYPERICUM PERFORATUM L. AND AMARANTHUS CAUDATUS L. ON FATTY STREAK FORMATION IN HYPERCHOLESTEROLEMIC RABBITS IN COMPARISON WITH LOVASTATIN. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS[Internet]. 2009;25(1 (43)):29-38. Available from: https://sid.ir/paper/104699/en

IEEE: Copy

NAJMEH KABIRI, SEDIGHEH ASGARY, HOSSEIN MADANI, P. MAHZOUNI, and PARIVASH RAHIMI, “THE EFFECT OF AERIAL PARTS OF CONCURRENT HYDROALCOHOLIC EXTRACTS OF HYPERICUM PERFORATUM L. AND AMARANTHUS CAUDATUS L. ON FATTY STREAK FORMATION IN HYPERCHOLESTEROLEMIC RABBITS IN COMPARISON WITH LOVASTATIN,” IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, vol. 25, no. 1 (43), pp. 29–38, 2009, [Online]. Available: https://sid.ir/paper/104699/en

Related Journal Papers