EFFECT OF ZATARIA MULTIFLORA BOISS. ESSENTIAL OILS ON PREVENTION OF LIVER INJURIES IN RATS TREATED WITH CARBON TETRACHLORIDE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ABDOLMOHAMMADI M.H.; DADKHAH A.; BABAEI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2016 | Volume:32 | Issue:1 (75) Page(s): 148-160

Download Full-Text

Persian Verion

View:

1,073

Download:

Cites:

Information Journal Paper

Title

EFFECT OF ZATARIA MULTIFLORA BOISS. ESSENTIAL OILS ON PREVENTION OF LIVER INJURIES IN RATS TREATED WITH CARBON TETRACHLORIDE

Author(s)

ABDOLMOHAMMADI M.H. | DADKHAH A. | BABAEI M. | Issue Writer Certificate

Keywords

ZATARIA MULTIFLORA BOISS.Q2

CARBON TETRACHLORIDEQ1

LIVERQ1

RATQ2

Abstract

Carbon tetra chloride converts to CCL3O by cytochrom P 450 that conjugate with glutathione by GST, leading to GSH depletion and oxidative injuries. Therefore, the compounds with antioxidant activity can prevent oxidative damages induced by CCL4. In this study, the RATs were divided into five groups treated with CCL4, (2ml/kg bw), essential oil (100 and 200 mg/kg bw) and BHT (10mg/kg bw) (ip). In following, the LIVER and blood were removed after administrations. The activity of GST, reduced glutathione (GSH), and lipid peroxidation (LP) levels were measured in LIVER homogenate. In addition, total antioxidant activity and the level of hepatic marker (AST, ALT, ALP and bilirubin) were measured in plasma of RATs. The results showed that CCL4 caused GSH depletion and reduction of GST activity in LIVER, leading to increased LIVER LP level and transaminase activities (AST and ALT) in plasma. Treatments of RATs with essential oil as same as BHT prevent the changes of these parameters. We can conclude that CCL4 induces hepatic oxidative damages in RATs. Treatment of RATs with essential oils, probably due to its antioxidant activity, can partly prevent the induction of LIVER injuries.

Cites

No record.

References

No record.

Cite

APA: Copy

ABDOLMOHAMMADI, M.H., DADKHAH, A., & BABAEI, M.. (2016). EFFECT OF ZATARIA MULTIFLORA BOISS. ESSENTIAL OILS ON PREVENTION OF LIVER INJURIES IN RATS TREATED WITH CARBON TETRACHLORIDE. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, 32(1 (75)), 148-160. SID. https://sid.ir/paper/104919/en

Vancouver: Copy

ABDOLMOHAMMADI M.H., DADKHAH A., BABAEI M.. EFFECT OF ZATARIA MULTIFLORA BOISS. ESSENTIAL OILS ON PREVENTION OF LIVER INJURIES IN RATS TREATED WITH CARBON TETRACHLORIDE. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS[Internet]. 2016;32(1 (75)):148-160. Available from: https://sid.ir/paper/104919/en

IEEE: Copy

M.H. ABDOLMOHAMMADI, A. DADKHAH, and M. BABAEI, “EFFECT OF ZATARIA MULTIFLORA BOISS. ESSENTIAL OILS ON PREVENTION OF LIVER INJURIES IN RATS TREATED WITH CARBON TETRACHLORIDE,” IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, vol. 32, no. 1 (75), pp. 148–160, 2016, [Online]. Available: https://sid.ir/paper/104919/en

Related Journal Papers