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Information Journal Paper

Title

Estimation Methods for Infertility Treatment Success: Comparison of Four Methods

Pages

  179-185

Abstract

 Objective: To analyze and compare four methods for estimating the chance of treatment success in infertile couples. Materials and methods: In a retrospective cohort study, information on demographic and clinical features, including age, body mass index (BMI), duration of inFertility, semen analysis, previous history of treatment and clinical examination of infertile couples were analyzed. Treatment success (childbearing) was calculated with four methods as live birth ratio, conditional probability and survival analysis (life table and Kaplan-Meyer method) and results are compared. Results: The Fertility ratio for the first treatment cycle was 29. 72% which decreased to 23. 13% by total treatment cycles. The success rate was 75. 4%. With conditional probability calculation at the end of the five treatment cycles. With the life table method in a five-year period, the probability for live birth was 78% and by Kaplan-Meyer method 73. 1% and the median of treatment time was 562 days. Conclusion: Calculation of inFertility treatment success rate by only simple live birth ratio of childbearing couples is associated with underestimation. Using the conditional probability method reduces that underestimation, but it is not considered the censored cases in the treatments. It seems life table (as a proxy of survival analysis) presents the closest estimation to clinical facts with considering the repetition of the treatment cycle and the duration of treatment.

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    APA: Copy

    ZARINARA, ALIREZA, KAMALI, KOOROSH, & AKHONDI, MOHAMMAD MAHDI. (2021). Estimation Methods for Infertility Treatment Success: Comparison of Four Methods. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, 15(3), 179-185. SID. https://sid.ir/paper/1053270/en

    Vancouver: Copy

    ZARINARA ALIREZA, KAMALI KOOROSH, AKHONDI MOHAMMAD MAHDI. Estimation Methods for Infertility Treatment Success: Comparison of Four Methods. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH[Internet]. 2021;15(3):179-185. Available from: https://sid.ir/paper/1053270/en

    IEEE: Copy

    ALIREZA ZARINARA, KOOROSH KAMALI, and MOHAMMAD MAHDI AKHONDI, “Estimation Methods for Infertility Treatment Success: Comparison of Four Methods,” JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, vol. 15, no. 3, pp. 179–185, 2021, [Online]. Available: https://sid.ir/paper/1053270/en

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