EFFECTIVENESS OF CARBAMAZEPINE IN THE CONTROL OF SECONDARY TONIC-CLONIC CONVULSIONS ON THE BASIS OF ABNORMAL UNDERLYING FINDINGS IN BRAIN CT SCAN OR MRI

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NIKSERESHT A.R.

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Journal: JOURNAL OF MEDICAL RESEARCH (JMR) Year:2003 | Volume:1 | Issue:3 Page(s): 26-33

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Title

EFFECTIVENESS OF CARBAMAZEPINE IN THE CONTROL OF SECONDARY TONIC-CLONIC CONVULSIONS ON THE BASIS OF ABNORMAL UNDERLYING FINDINGS IN BRAIN CT SCAN OR MRI

Author(s)

NIKSERESHT A.R. | Issue Writer Certificate

Keywords

CARBAMAZEPINEQ4

SECONDARY TONIC-CLONIC CONVULSIONQ4

EFFICACYQ2

Abstract

Background: CARBAMAZEPINE is one of the most effective anticonvulsant drugs for tonic-clonic convulsions, with a daily maintenance dose of 600-1600 mg. Materials and Methods: Over a 5-year period, from 1997to 2002, brain CT scan and/or MRI of 1832 epileptic patients with an age range of 18-70 years were reviewed. All of the patients had tonic-clonic convulsion and only used CARBAMAZEPINE. Results: Out of 1832 patients, 496 (315 males, 181females) had abnormal findings in CT and/or MRl including cerebrovascular disease, idiopathic atrophy, brain trauma, primary brain tumors, post-encephalitic findings, gliosis, brain vasculitis, idiopathic calcification, porencephaly and findings related to neurocutaneous syndromes. Effectiveness of CARBAMAZEPINE in the control of symptomatic seizures were graded into 3 categories. Good; for control of seizures due to calcification, gliosis, trauma, cerebrovascular accident and idiopathic atrophy. Moderate; for control of seizures due to tumors,encephalitis, vasculitis and neurocutaneous syndromes.Poor; for control of seizures due to porencephaly. Conclusion: About 70% of patients with abnormal findings in brain CT scan and/or MRI were controlled by CARBAMAZEPINE. CARBAMAZEPINE is not a suitable drug in the control of tonic-clonic convulsions in porencephaly.

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APA: Copy

NIKSERESHT, A.R.. (2003). EFFECTIVENESS OF CARBAMAZEPINE IN THE CONTROL OF SECONDARY TONIC-CLONIC CONVULSIONS ON THE BASIS OF ABNORMAL UNDERLYING FINDINGS IN BRAIN CT SCAN OR MRI. JOURNAL OF MEDICAL RESEARCH (JMR), 1(3), 26-33. SID. https://sid.ir/paper/105825/en

Vancouver: Copy

NIKSERESHT A.R.. EFFECTIVENESS OF CARBAMAZEPINE IN THE CONTROL OF SECONDARY TONIC-CLONIC CONVULSIONS ON THE BASIS OF ABNORMAL UNDERLYING FINDINGS IN BRAIN CT SCAN OR MRI. JOURNAL OF MEDICAL RESEARCH (JMR)[Internet]. 2003;1(3):26-33. Available from: https://sid.ir/paper/105825/en

IEEE: Copy

A.R. NIKSERESHT, “EFFECTIVENESS OF CARBAMAZEPINE IN THE CONTROL OF SECONDARY TONIC-CLONIC CONVULSIONS ON THE BASIS OF ABNORMAL UNDERLYING FINDINGS IN BRAIN CT SCAN OR MRI,” JOURNAL OF MEDICAL RESEARCH (JMR), vol. 1, no. 3, pp. 26–33, 2003, [Online]. Available: https://sid.ir/paper/105825/en

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