CU/ZN SUPEROXIDE DISMUTASEENZYME OF LYMPHOCYTIC CELL GENE EXPRESSION, TOTAL ANTIOXIDANT STATUS AND OXIDATIVE STRESS VARIATION FALLOWING TO INTENSIVE EXERCISE IN YOUNG MEN ATHLETES

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BAGHAIEE BEHROOZ; TARTIBIAN BAKHTIAR; ALIPARASTY MOHAMMAD REZA; BARADARAN BEHZAD; ALMASY SHOHREH

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Journal: Razi Journal of Medical Sciences Year:2012 | Volume:19 | Issue:95 Page(s): 1-9

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Title

CU/ZN SUPEROXIDE DISMUTASEENZYME OF LYMPHOCYTIC CELL GENE EXPRESSION, TOTAL ANTIOXIDANT STATUS AND OXIDATIVE STRESS VARIATION FALLOWING TO INTENSIVE EXERCISE IN YOUNG MEN ATHLETES

Author(s)

Keywords

CU/ZN SOD MRNAQ2

TASQ1

H2O2Q2

MEN ATHLETESQ2

Abstract

Background: The aim of this research is investigation of Cu/Zn Superoxide Dismutase enzyme of lymphocytic cell gene expression, total antioxidant status and oxidative stress changes following intensive exercise in young MEN ATHLETES.Methods: This study was a semi-experimental research with a repeated measures design. 20 young MEN ATHLETES (age range of 21-23 years) participated in this study after signing an informed consent form. Blood sample were collected in pre intensive exercise (grade: 5%, speed: 7.5 mile/h, time: 20 minutes) immediately and recovery (3 hours after exercise test), and Real time-polymerase chain reaction was used for evaluation of Cu/Zn SOD gene expression and autoanalyzer for other markers.Results: H2O2 level and mRNA of Cu/Zn SOD were both increased, immediately and 3 hours after of exercise (p=0.012, p=0.014), (2.95±0.84 and 3.37±0.99) but this changes were not reported significant, but TAS levels areeffectively, raised only in recovery state (p=0.009) (0.86±0.16).Conclusions: Intensive exercise increases oxidative stress markers and can weakens the immune system of MEN ATHLETES, but they raisethe activity of antioxidant enzymes in response to threat of free radicals, so Cu/Zn SOD gene expression does not significantly increased.

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EFFECT OF OXIDATIVE STRESS AND EXERCISE-INDUCED ADAPTATIONS (REVIEW ARTICLE)

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APA: Copy

BAGHAIEE, BEHROOZ, TARTIBIAN, BAKHTIAR, ALIPARASTY, MOHAMMAD REZA, BARADARAN, BEHZAD, & ALMASY, SHOHREH. (2012). CU/ZN SUPEROXIDE DISMUTASEENZYME OF LYMPHOCYTIC CELL GENE EXPRESSION, TOTAL ANTIOXIDANT STATUS AND OXIDATIVE STRESS VARIATION FALLOWING TO INTENSIVE EXERCISE IN YOUNG MEN ATHLETES. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 19(95), 1-9. SID. https://sid.ir/paper/10584/en

Vancouver: Copy

BAGHAIEE BEHROOZ, TARTIBIAN BAKHTIAR, ALIPARASTY MOHAMMAD REZA, BARADARAN BEHZAD, ALMASY SHOHREH. CU/ZN SUPEROXIDE DISMUTASEENZYME OF LYMPHOCYTIC CELL GENE EXPRESSION, TOTAL ANTIOXIDANT STATUS AND OXIDATIVE STRESS VARIATION FALLOWING TO INTENSIVE EXERCISE IN YOUNG MEN ATHLETES. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2012;19(95):1-9. Available from: https://sid.ir/paper/10584/en

IEEE: Copy

BEHROOZ BAGHAIEE, BAKHTIAR TARTIBIAN, MOHAMMAD REZA ALIPARASTY, BEHZAD BARADARAN, and SHOHREH ALMASY, “CU/ZN SUPEROXIDE DISMUTASEENZYME OF LYMPHOCYTIC CELL GENE EXPRESSION, TOTAL ANTIOXIDANT STATUS AND OXIDATIVE STRESS VARIATION FALLOWING TO INTENSIVE EXERCISE IN YOUNG MEN ATHLETES,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 19, no. 95, pp. 1–9, 2012, [Online]. Available: https://sid.ir/paper/10584/en

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