ADENYLYL CYCLAS EASSAY TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION

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GHOUJEGH D.; AHMADI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Razi Journal of Medical Sciences Year:2001 | Volume:8 | Issue:25 Page(s): 283-287

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Information Journal Paper

Title

ADENYLYL CYCLAS EASSAY TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION

Author(s)

GHOUJEGH D. | AHMADI M. | Issue Writer Certificate

Keywords

ADENYLYL CYCLASEQ4

MACROPHAGE CHEMOTACTIC PROTEIN-1Q4

Abstract

The purpose of this investigation was to determine the ADENYLYL CYCLASE activity for evaluating the role of macrophage chemotactic protein. ADENYLYL CYCLASE is a membrane-bound enzyme that catalyzes the conversion of ATP to cAMP. The inhibition of ADENYLYL CYCLASE was carried out by measuring the ability of the MACROPHAGE CHEMOTACTIC PROTEIN-1 to inhibit the forskolin-induced enzyme activity. Measurement of ADENYLYL CYCLASE activity was performed according to the procedure described by Wiegn.ADENYLYL CYCLASE activity in the present MACROPHAGE CHEMOTACTIC PROTEIN-1 was decreased compared to that in controls [2.11± 0.15(mean± SD.)vs. 6.83±0.45, activity (µmol cAMP/mg protein/min)]. Macrophage chemotactic protein significantly reduced ADENYLYL CYCLASE activity by 79.9%.

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APA: Copy

GHOUJEGH, D., & AHMADI, M.. (2001). ADENYLYL CYCLAS EASSAY TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 8(25), 283-287. SID. https://sid.ir/paper/10717/en

Vancouver: Copy

GHOUJEGH D., AHMADI M.. ADENYLYL CYCLAS EASSAY TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2001;8(25):283-287. Available from: https://sid.ir/paper/10717/en

IEEE: Copy

D. GHOUJEGH, and M. AHMADI, “ADENYLYL CYCLAS EASSAY TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 8, no. 25, pp. 283–287, 2001, [Online]. Available: https://sid.ir/paper/10717/en

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