Evaluation of peritoneal fluid and serum soluble Fas ligand (sFasL) levels in women with endometriosis compared to non-endometriotic controls

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOHAMMADI TAHEREH; Delbandi Ali Akbar; MORADI ZAHRA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2018 | Volume:25 | Issue:9 Page(s): 66-72

Download Full-Text

Persian Verion

View:

883

Download:

Cites:

Information Journal Paper

Title

Evaluation of peritoneal fluid and serum soluble Fas ligand (sFasL) levels in women with endometriosis compared to non-endometriotic controls

Author(s)

MOHAMMADI TAHEREH | Delbandi Ali Akbar | MORADI ZAHRA | Issue Writer Certificate

Keywords

EndometriosisQ2

Soluble FasLQ1

ApoptosisQ1

Abstract

Background: Endometriosis is a common gynecological disorder, which its main feature is the growth of endometrial tissue outside the uterine cavity. In this disease, Apoptosis is impaired in endometrial cells transmitted to the peritoneal cavity, and thus these cells remain in ectopic sites and grow there. FasL-expressing cells induce Apoptosis when they bind to Fas-bearing immune cells. Soluble Fas ligand can be proteolytically cleaved from membrane-bound Fas ligand by metalloproteinases. Studies show that both soluble and membranous form of FasL in peritoneal cavity of endometriotic women can induce Apoptosis of Fas bearing immune cells. Therefore, in this study the serum and peritoneal fluid levels of sFasL in patients with Endometriosis compared with non-endometriotic subjects were evaluated. Methods: In this case-control study, which was performed from 2016 to 2017, peritoneal cavity of 19 patients with Endometriosis and 19 healthy subjects, and also serum of 16 patients with Endometriosis and 12 healthy subjects were studied. ELISA were used to determine the sFasL. Results: The results of this study showed that the amount of sFasL in peritoneal cavity of Endometriosis patients is higher than healthy group, but this difference was not statistically significant (p=0. 07). Also, the serum sFasL level of patients was not different from control group. Conclusion: Expression of high sFasL in the peritoneal fluid can be one of the factors involved in the removal of Fas-expressing immune cells in the peritoneal fluid, which plays an essential role in the progression of the disease.

Cites

No record.

References

Fas-related apoptosis of peritoneal fluid macrophages in endometriosis patients: understanding the disease

Cite

APA: Copy

MOHAMMADI, TAHEREH, Delbandi, Ali Akbar, & MORADI, ZAHRA. (2018). Evaluation of peritoneal fluid and serum soluble Fas ligand (sFasL) levels in women with endometriosis compared to non-endometriotic controls. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 25(9 ), 66-72. SID. https://sid.ir/paper/10950/en

Vancouver: Copy

MOHAMMADI TAHEREH, Delbandi Ali Akbar, MORADI ZAHRA. Evaluation of peritoneal fluid and serum soluble Fas ligand (sFasL) levels in women with endometriosis compared to non-endometriotic controls. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2018;25(9 ):66-72. Available from: https://sid.ir/paper/10950/en

IEEE: Copy

TAHEREH MOHAMMADI, Ali Akbar Delbandi, and ZAHRA MORADI, “Evaluation of peritoneal fluid and serum soluble Fas ligand (sFasL) levels in women with endometriosis compared to non-endometriotic controls,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 25, no. 9 , pp. 66–72, 2018, [Online]. Available: https://sid.ir/paper/10950/en

Related Journal Papers