مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

33
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

26
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Effectiveness of Moderate-intensity Continuous Training and Nanocurcumin Supplementation on Sensorimotor Disorders in Rats With Brain Tumors

Pages

  894-909

Abstract

 Background and Objectives Abnormal growth of brain cells can lead to the formation of tumor cell masses and disruption of normal brain functions, including sensory-motor functions. The present study aims to evaluate the effectiveness of moderate-intensity continuous training (MICT) and Nanocurcumin supplementation on sensorimotor disorders in rats with Brain tumors. Subjects and Methods In this study, 35 healthy male Wistar rats were randomly divided into 7 groups of 5, including baseline control (BC), 4-week control (4wC), baseline tumor control (BT), 4-week tumor control (4wT), tumor exercise (TE), tumor nanocurcumin (TN), tumor exercise+nanocurcumin (TEN). One week after the injection of cancer cells in the frontal cortex and performing a 6-parameter behavioral test (Garcia scale), the rats in the TEN and TN groups received Nanocurcumin supplement by gavage at a dose of 80 mg/kg (28 days, 5 days a week). Then, the rats in the TE and TEN groups performed the MICT on a treadmill for 4 weeks, at a speed of 18 m/min, 3 days a week, each for 25-40 minutes. Finally, the rats were sacrificed and data were collected and analyzed. Results The MICT plus Nanocurcumin supplementation significantly reduced tumor volume in the TEN group (P≤, 0. 05). It also led to a significant increase in the behavioral test score in the groups TE, TN and TEN compared to the 4wT group. Conclusion It seems that the combination of MICT with Nanocurcumin supplementation can be used as a complementary method along with other methods to reduce Brain tumor volume and improve sensory-motor functions.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    HAJINAJAF, SAEEDEH, SHIRVANI, HOSSEIN, ROOZBAHANI, MEHDI, & Khademi, Alireza. (2023). Effectiveness of Moderate-intensity Continuous Training and Nanocurcumin Supplementation on Sensorimotor Disorders in Rats With Brain Tumors. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 21(6 ), 894-909. SID. https://sid.ir/paper/1100321/en

    Vancouver: Copy

    HAJINAJAF SAEEDEH, SHIRVANI HOSSEIN, ROOZBAHANI MEHDI, Khademi Alireza. Effectiveness of Moderate-intensity Continuous Training and Nanocurcumin Supplementation on Sensorimotor Disorders in Rats With Brain Tumors. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2023;21(6 ):894-909. Available from: https://sid.ir/paper/1100321/en

    IEEE: Copy

    SAEEDEH HAJINAJAF, HOSSEIN SHIRVANI, MEHDI ROOZBAHANI, and Alireza Khademi, “Effectiveness of Moderate-intensity Continuous Training and Nanocurcumin Supplementation on Sensorimotor Disorders in Rats With Brain Tumors,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 21, no. 6 , pp. 894–909, 2023, [Online]. Available: https://sid.ir/paper/1100321/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button