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Information Journal Paper

Title

Investigating the Apoptotic Effect of Oxygen, Ozone and Air Nano microbubbles on Melanoma Cell Line

Pages

  1302-1312

Abstract

 Introduction: Skin melanoma is one of the most invasive types of skin cancer. It accounts for about 75% of all skin cancer deaths and has not yet been definitively treated. As a result, early diagnosis and prevention of the disease is important. Much research has been done to find ways to treat and cure cancer. One of the newest methods in this field is the use of nanotechnology to detect and inhibit cancer cells. In this study, the effect of using Nano microbubbles of Air, Oxygen and Ozone on A375 Melanoma cancer cell line was evaluated. Materials and Methods: A375 cell line treated with different concentrations of Nano microbubbles of Air, Oxygen and Ozone and were evaluated by MTT method. In order to measure cell viability, MTT plate was added to each well and then the plate was incubated. Results: According to the results of this study, a decrease in the viability of A375 cancer cells with an increase in the concentration of Oxygen and Ozone Nano microbubbles after 24 hours indicates apoptosis and has a significant inhibition of the growth of these cells. Conclusion: The results of this study indicate that Nano microbubbles of Oxygen and Ozone in high concentrations cause cell death of A375 cell line. The results of this study will help investigate the role of Nano microbubbles of Air, Oxygen and Ozone in the treatment of Melanoma cancer.

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    Cite

    APA: Copy

    Fazeli, Fateme, sadeghifar, Fateme, & RAHIMI, HAMID REZA. (2022). Investigating the Apoptotic Effect of Oxygen, Ozone and Air Nano microbubbles on Melanoma Cell Line. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 65(3 ), 1302-1312. SID. https://sid.ir/paper/1126789/en

    Vancouver: Copy

    Fazeli Fateme, sadeghifar Fateme, RAHIMI HAMID REZA. Investigating the Apoptotic Effect of Oxygen, Ozone and Air Nano microbubbles on Melanoma Cell Line. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2022;65(3 ):1302-1312. Available from: https://sid.ir/paper/1126789/en

    IEEE: Copy

    Fateme Fazeli, Fateme sadeghifar, and HAMID REZA RAHIMI, “Investigating the Apoptotic Effect of Oxygen, Ozone and Air Nano microbubbles on Melanoma Cell Line,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 65, no. 3 , pp. 1302–1312, 2022, [Online]. Available: https://sid.ir/paper/1126789/en

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