EXPERIMENTAL STUDY OF PENTOXIFYLLINE IN PREVENTION OF POST - OPERATIVE INTRAPERITONEAL ADHESION BAND

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DAVARI H.A.; GOHARIAN V.; EGHBAL A.P.

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Journal: Iranian Journal of Surgery Year:2005 | Volume:13 | Issue:2 (35) Page(s): 22-27

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Title

EXPERIMENTAL STUDY OF PENTOXIFYLLINE IN PREVENTION OF POST - OPERATIVE INTRAPERITONEAL ADHESION BAND

Author(s)

DAVARI H.A. | GOHARIAN V. | EGHBAL A.P. | Issue Writer Certificate

Keywords

PENTOXIFYLLINEQ4

ADHESION BANDSQ4

RATQ3

Abstract

Introduction & Objective: Intraperitoneal ADHESION BANDS which usually occur after previous abdominal surgery, is one of the most important causes of bowel obstruction. It can be as a morbid condition for long life. Therefore, any research for its prevention after abdominal surgery can improve length and quality of life of patients.Materials & Methods: In an experimental study, 30 male RATs (mean weight: 220±20 gr) were selected and divided in two equal groups (case and control) randomly. After anesthesia with ketamin laparatomy was performed. A segment of left peritoneal wall was removed and longitudinal incisions was performed on right side of abdominal peritoneum.After operation, in cases group PENTOXIFYLLINE tablet was added to regimen. Two weeks later, laparatomy was performed with previous technique and severity of adhesions was evaluated.Mann-Whitney test analysis was used for evaluation.Results: Three RATs were died from control group. Mean of adhesion scores was 2.5±0.9 in controls and 1.06±0.866 in case group (P<0.05).Conclusions: PENTOXIFYLLINE can decrease adhesion band formation after abdominal surgery in RATs. For its effects on human, more research should be done.

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APA: Copy

DAVARI, H.A., GOHARIAN, V., & EGHBAL, A.P.. (2005). EXPERIMENTAL STUDY OF PENTOXIFYLLINE IN PREVENTION OF POST - OPERATIVE INTRAPERITONEAL ADHESION BAND. IRANIAN JOURNAL OF SURGERY, 13(2 (35)), 22-27. SID. https://sid.ir/paper/112882/en

Vancouver: Copy

DAVARI H.A., GOHARIAN V., EGHBAL A.P.. EXPERIMENTAL STUDY OF PENTOXIFYLLINE IN PREVENTION OF POST - OPERATIVE INTRAPERITONEAL ADHESION BAND. IRANIAN JOURNAL OF SURGERY[Internet]. 2005;13(2 (35)):22-27. Available from: https://sid.ir/paper/112882/en

IEEE: Copy

H.A. DAVARI, V. GOHARIAN, and A.P. EGHBAL, “EXPERIMENTAL STUDY OF PENTOXIFYLLINE IN PREVENTION OF POST - OPERATIVE INTRAPERITONEAL ADHESION BAND,” IRANIAN JOURNAL OF SURGERY, vol. 13, no. 2 (35), pp. 22–27, 2005, [Online]. Available: https://sid.ir/paper/112882/en

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