Biobased Polylactide Nanoparticles as Novel Gene Delivery Nanoplatforms: Can They Be Used for DNA Transport?

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Fattahi Farnaz Sadat

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Nanochemistry Research Year:2024 | Volume:9 | Issue:2 Page(s): 146-152

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Biobased Polylactide Nanoparticles as Novel Gene Delivery Nanoplatforms: Can They Be Used for DNA Transport?

Author(s)

Fattahi Farnaz Sadat | Issue Writer Certificate

Keywords

DNA

Polylactide

Gene delivery

Nanoparticle

Abstract

Gene therapy is a rapidly progressing field with vast prospective for fundamentally treating human diseases such as cancer, damaged tissues, and genetic syndromes. Between various approaches of Gene delivery, there is a growing interest in oral administration of DNA as one of the safest and most straightforward methods. Nanoparticles are some of the important examples of nano-materials for molecule delivery (drugs, growth factors and DNA) used in biomedical applications. Several researchers have revealed the process of nanotechnology, specifically polymeric Nanoparticles, as DNA delivery structures for transdermal routines. Polylactic acid (PLA) and its famous co-polymer polylactic-co-glycolic (PLGA) are biocompatible synthetic polymers widely used to produce Nanoparticles. Biobased, biosourced, biodegradable biocompatible, and bioabsorbable Polylactide Nanoparticles are one of the most promising materials in gene therapy serving as DNA delivery vehicles. Polylactide Nanoparticles are easily processable and undergo degradation into natural metabolites while matching its degradation rate with the healing time of damaged human tissues. This mini review presents the new developments in the applications of Polylactide Nanoparticles as DNA delivery systems. In addition, the release of DNA from these nanoplatforms will be reported briefly.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans