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Information Journal Paper

Title

STUDY ABCG2 GENE POLYMORPHISM IN IRANIAN HOLSTEIN BULLS

Pages

  141-145

Keywords

Not Registered.

Abstract

 ABCG2 (ATP binding cassette subfamily G member 2) gene have located in chromosome 6 which is encoded ABCG2 protein that transports various xenobiotics, cytostatic drugs across the plasma membrane and cholesterol into milk. A single nucleotide change (A/C) in base 86 of exon 14 is capable of encoding a substitution of tyrosine to serine in the ABCG2 gene and increases milk yield and decreases fat and protein concentration. The major aim of this research is to identify ABCG2 gene polymorphism in Iranian population of Holstein bulls. Genomic DNA of 105 bulls was extracted from semen samples using high Pure PCR template preparation kit. Primers were designed with Oligo software and utilized in PCR. Then the PCR fragments were sequenced. Results of sequences were compared with NCBI sequence databases. A/C mutation in base 86 of exon 14 was observed with 2% frequency.ABCG2 gene, Iranian Holstein bulls, Polymorphism.

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    • References

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    • Cite

    APA: Copy

    MOUSAVIZADEH, ALI, SALEHI, ABDOLREZA, AMINAFSHAR, MEHDI, & NAZEMSHIRAZI, MOHAMMADHOSSEIN. (2012). STUDY ABCG2 GENE POLYMORPHISM IN IRANIAN HOLSTEIN BULLS. MODERN GENETICS JOURNAL (MGJ), 7(2 (29)), 141-145. SID. https://sid.ir/paper/116409/en

    Vancouver: Copy

    MOUSAVIZADEH ALI, SALEHI ABDOLREZA, AMINAFSHAR MEHDI, NAZEMSHIRAZI MOHAMMADHOSSEIN. STUDY ABCG2 GENE POLYMORPHISM IN IRANIAN HOLSTEIN BULLS. MODERN GENETICS JOURNAL (MGJ)[Internet]. 2012;7(2 (29)):141-145. Available from: https://sid.ir/paper/116409/en

    IEEE: Copy

    ALI MOUSAVIZADEH, ABDOLREZA SALEHI, MEHDI AMINAFSHAR, and MOHAMMADHOSSEIN NAZEMSHIRAZI, “STUDY ABCG2 GENE POLYMORPHISM IN IRANIAN HOLSTEIN BULLS,” MODERN GENETICS JOURNAL (MGJ), vol. 7, no. 2 (29), pp. 141–145, 2012, [Online]. Available: https://sid.ir/paper/116409/en

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