BIOTECHNOLOGY FOR LARGE SCALE PRODUCTION OF PLANTS SECONDARY METABOLITES

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OMIDI M.; ABDOLLAHI P.

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Paper Information

Journal: MODERN GENETICS JOURNAL (MGJ) Year:2015 | Volume:9 | Issue:4 (39) Page(s): 391-402

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Title

BIOTECHNOLOGY FOR LARGE SCALE PRODUCTION OF PLANTS SECONDARY METABOLITES

Author(s)

OMIDI M. | ABDOLLAHI P. | Issue Writer Certificate

Keywords

BIOREACTORSQ1

ELICITORSQ2

LARGE SCALE PRODUCTIONQ1

METABOLIC ENGINEERINGQ1

TISSUE CULTUREQ2

Abstract

Plants produce variety of secondary metabolites which are economically important as drugs, flavor and fragrances, dye and pigments, pesticides, and etc. Several problems such as level of production, heterogeneous quality and raw material supply affect production of secondary metabolites in plants. The growing demands in today’s market place for renewable natural products lead scientist to consider in vitro plants material cultures as an alternative method for production of secondary phytochemicals. Plant cell culture and TISSUE CULTURE under sterile condition have been used to produce and extract plants secondary metabolites and multiplication. However, most of trails fail to produce desired products and new strategies to improve production of secondary metabolites are needed. ELICITORS including biotic and abiotic compounds, trigger formation of secondary metabolites. Phytohormones such as methyl jasmonate and gibberellic acid and polysaccharides such as chitosan have been used as biotic ELICITORS. Helium-neon soft laser and ultrasonic are examples of abiotic ELICITORS. Lack of enough knowledge about biosynthetic pathways and mechanisms involve in plant metabolite production is one of the main problems in production of secondary metabolites. Where the productivity of the desired metabolites is limited by the lack of particular precursors, biotransformation using an exogenous supply of biosynthetic precursors, genetic manipulation and METABOLIC ENGINEERING may improve the accumulation of compounds. Amino acids are commonly used as secondary metabolite precursors. Any foreign gene of interest can be transferred to hairy root clones in order to produce genetically modified hairy roots and improve the production of secondary metabolites. Cell immobilization in calcium alginate along with suitable bioreactor system can enhance the production of secondary metabolites in vitro. The present review is covering biotechnological methods and useful applications to optimize and scale up production of plant secondary metabolite.

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APA: Copy

OMIDI, M., & ABDOLLAHI, P.. (2015). BIOTECHNOLOGY FOR LARGE SCALE PRODUCTION OF PLANTS SECONDARY METABOLITES. MODERN GENETICS JOURNAL (MGJ), 9(4 (39)), 391-402. SID. https://sid.ir/paper/116689/en

Vancouver: Copy

OMIDI M., ABDOLLAHI P.. BIOTECHNOLOGY FOR LARGE SCALE PRODUCTION OF PLANTS SECONDARY METABOLITES. MODERN GENETICS JOURNAL (MGJ)[Internet]. 2015;9(4 (39)):391-402. Available from: https://sid.ir/paper/116689/en

IEEE: Copy

M. OMIDI, and P. ABDOLLAHI, “BIOTECHNOLOGY FOR LARGE SCALE PRODUCTION OF PLANTS SECONDARY METABOLITES,” MODERN GENETICS JOURNAL (MGJ), vol. 9, no. 4 (39), pp. 391–402, 2015, [Online]. Available: https://sid.ir/paper/116689/en

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