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Information Journal Paper

Title

A STUDY ON THE EFFECTIVENESS OF LOVASTATIN IN INCREASING MUSCULAR POWER IN PATIENTS WITH THROMBOTIC CVA IN SUPERIOR BRANCH OF MIDDLE CEREBRAL ARTERY

Pages

  100-105

Abstract

 Objective: Stroke one of the most common diseases in neurology and is the third cause of death in old age. Impairment of motor power and other neurological deficits and imposes a significant financial burden on both patients' family and health care system. The aim of the present study was to assess the effectiveness in improving the muscular power among these patients.Subjects and Methods: In this study on 100 patients (50 females and 50 males) diagnosed by history, physical examination and brain CT-scan who had experienced THROMBOTIC CVA on superior branch of the middle cerebral artery and had a normal lipid profile on laboratory examination and did not previously receive LOVASTATIN therapy, were allocated into LOVASTATIN and control groups. The LOVASTATIN group (n= 49; 22 males and 27 females) received 20 mg/day for one month. While the control group (n= 51; 28 males and 24 females). Both groups received usual standard treatment of THROMBOTIC CVA (ASA 325mg/daily and dipyridamol 25mg/tds) and similar physiotherapy interventions. The MUSCLE POWER at first, one week and 30 days after starting trial on each patient was measured with the same NIHSS scaling.Results: Both groups had some improvement at the end of trial but patients received LOVASTATIN had a significantly better improvement (P<0.001). In the LOVASTATIN treated group, better improvement was observed among younger patients (51-65). There was no significant statistical correlation between sex and weight with response to treatment. Conclusion: The finding of this study confirms previous clinical trials and suggests that LOVASTATIN improved MUSCLE POWER in THROMBOTIC CVA patients.

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    APA: Copy

    MAJDINASAB, N., & SHARAF ALDINZADEH, N.. (2008). A STUDY ON THE EFFECTIVENESS OF LOVASTATIN IN INCREASING MUSCULAR POWER IN PATIENTS WITH THROMBOTIC CVA IN SUPERIOR BRANCH OF MIDDLE CEREBRAL ARTERY. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 7(1 (56)), 100-105. SID. https://sid.ir/paper/12538/en

    Vancouver: Copy

    MAJDINASAB N., SHARAF ALDINZADEH N.. A STUDY ON THE EFFECTIVENESS OF LOVASTATIN IN INCREASING MUSCULAR POWER IN PATIENTS WITH THROMBOTIC CVA IN SUPERIOR BRANCH OF MIDDLE CEREBRAL ARTERY. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2008;7(1 (56)):100-105. Available from: https://sid.ir/paper/12538/en

    IEEE: Copy

    N. MAJDINASAB, and N. SHARAF ALDINZADEH, “A STUDY ON THE EFFECTIVENESS OF LOVASTATIN IN INCREASING MUSCULAR POWER IN PATIENTS WITH THROMBOTIC CVA IN SUPERIOR BRANCH OF MIDDLE CEREBRAL ARTERY,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 7, no. 1 (56), pp. 100–105, 2008, [Online]. Available: https://sid.ir/paper/12538/en

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