THE EFFECT OF 4 WEEKS OF FLAXSEED EXTRACT SUPPLEMENTATION ON SERUM CONCENTRATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND C-REACTIVE PROTEIN

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NAZARI HOSSEIN; TAHMASBPOUR EISA; FALLAH MOHAMMADI ZIYA; MOHAMMADPOUR GHASEM; RAHIMIZADEH SHAMSEDDIN

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Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2017 | Volume:10 | Issue:11 Page(s): 9-16

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Title

THE EFFECT OF 4 WEEKS OF FLAXSEED EXTRACT SUPPLEMENTATION ON SERUM CONCENTRATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND C-REACTIVE PROTEIN

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Keywords

BRAIN-DERIVED NEUROTROPHIC FACTORQ1

C-REACTIVE PROTEINQ1

FLAXQ1

OMEGA-3Q1

Abstract

Background and Objective: OMEGA-3 Supplementation has different effects on the body. Terefore, this study was carried out with the aim of investigating the effect of 4 weeks of FLAXseed extract supplementation on serum concentrations of BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) and C-REACTIVE PROTEIN (CRP).Methods: In this double-blind study, 24 male students (mean age, 23.21±1.98) were randomly divided into two groups, including FLAXseed extract (n=12) and placebo (n=12). After 4 weeks of supplementation with FLAXseed extract, serum levels of BDNF and CRP was measured in fasting state. BDNF level was measured using an enzyme-linked immunosorbent assay (ELISA) kit, and CRP level was measured using an immunoturbidimetric assay kit. Data were analyzed using t-test. The level of significance was set at p<0.05.Results: After four weeks of supplementation with FLAXseed extract the mean serum level of BDNF significantly increased (p<0.001), but no significant change was observed in the serum level of CRP (p<0.591).Conclusion: It seems that supplementation with FLAXseed extract through increasing BDNF level is useful for the improvement of cognitive and functional benefits of the brain.

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APA: Copy

NAZARI, HOSSEIN, TAHMASBPOUR, EISA, FALLAH MOHAMMADI, ZIYA, MOHAMMADPOUR, GHASEM, & RAHIMIZADEH, SHAMSEDDIN. (2017). THE EFFECT OF 4 WEEKS OF FLAXSEED EXTRACT SUPPLEMENTATION ON SERUM CONCENTRATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND C-REACTIVE PROTEIN. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 10(11), 9-16. SID. https://sid.ir/paper/132020/en

Vancouver: Copy

NAZARI HOSSEIN, TAHMASBPOUR EISA, FALLAH MOHAMMADI ZIYA, MOHAMMADPOUR GHASEM, RAHIMIZADEH SHAMSEDDIN. THE EFFECT OF 4 WEEKS OF FLAXSEED EXTRACT SUPPLEMENTATION ON SERUM CONCENTRATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND C-REACTIVE PROTEIN. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2017;10(11):9-16. Available from: https://sid.ir/paper/132020/en

IEEE: Copy

HOSSEIN NAZARI, EISA TAHMASBPOUR, ZIYA FALLAH MOHAMMADI, GHASEM MOHAMMADPOUR, and SHAMSEDDIN RAHIMIZADEH, “THE EFFECT OF 4 WEEKS OF FLAXSEED EXTRACT SUPPLEMENTATION ON SERUM CONCENTRATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND C-REACTIVE PROTEIN,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 10, no. 11, pp. 9–16, 2017, [Online]. Available: https://sid.ir/paper/132020/en

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