ANTIFUNGAL EFFECTS OF GOLD NANOPARTICLES CONJUGATED FLUCONAZOLE AGAINST FLUCONAZOLE RESISTANT STRAINS OF CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH CHRONIC VULVOVAGINITIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MEMARIAN MEHRDAD; JAVADI ALI; FATEH ROOHOLLAH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Qom University of Medical Sciences Journal Year:2016 | Volume:10 | Issue:7 Page(s): 10-19

Download Full-Text

Persian Verion

View:

926

Download:

Cites:

Information Journal Paper

Title

ANTIFUNGAL EFFECTS OF GOLD NANOPARTICLES CONJUGATED FLUCONAZOLE AGAINST FLUCONAZOLE RESISTANT STRAINS OF CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH CHRONIC VULVOVAGINITIS

Author(s)

MEMARIAN MEHRDAD | JAVADI ALI | FATEH ROOHOLLAH | Issue Writer Certificate

Keywords

RECURRENT VAGINITISQ1

CANDIDA ALBICANSQ1

NANOPARTICLESQ1

FLUCONAZOLEQ1

Abstract

Background and Objectives: A number of women with volvuvaginal candidiasis suffer from certain chronic and recurrent types of this infection that affect their quality of life. Meanwhile, increased use of antifungal drugs, especially azoles, for treatment of chronic candidiasis is an important factor for incidence of drug resistance in Candida isolates from patients with vulvovaginal candidiasis. The aim of this study was to investigate anticandidal effects of gold NANOPARTICLES conjugated FLUCONAZOLE to develop better drugs for treatment of patients with candidal vaginitis, especially its chronic type.Methods: After collection of 300 vaginal swab specimens and culture and isolation of primary colonies and determination of Candida species, FLUCONAZOLE resistant strains of CANDIDA ALBICANS were detected using disc diffusion. Finally, antifungal effects of gold NANOPARTICLES conjugated FLUCONAZOLE and FLUCONAZOLE were compared by broth microdilution.Results: Only one FLUCONAZOLE resistant strain of C. albicans was isolated from patients (MIC=64 mg/ml). The results obtained from drug susceptibility test showed that this strain was sensitive to gold NANOPARTICLES conjugated FLUCONAZOLE (MIC=2 mg/ml).Conclusion: Given the optimal anticandidal effects of gold NANOPARTICLES conjugated FLUCONAZOLE on resistant strains of C. albicans, a suitable compound with great anticandidal properties may be achieved in the future.

Cites

No record.

References

No record.

Cite

APA: Copy

MEMARIAN, MEHRDAD, JAVADI, ALI, & FATEH, ROOHOLLAH. (2016). ANTIFUNGAL EFFECTS OF GOLD NANOPARTICLES CONJUGATED FLUCONAZOLE AGAINST FLUCONAZOLE RESISTANT STRAINS OF CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH CHRONIC VULVOVAGINITIS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 10(7), 10-19. SID. https://sid.ir/paper/132246/en

Vancouver: Copy

MEMARIAN MEHRDAD, JAVADI ALI, FATEH ROOHOLLAH. ANTIFUNGAL EFFECTS OF GOLD NANOPARTICLES CONJUGATED FLUCONAZOLE AGAINST FLUCONAZOLE RESISTANT STRAINS OF CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH CHRONIC VULVOVAGINITIS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2016;10(7):10-19. Available from: https://sid.ir/paper/132246/en

IEEE: Copy

MEHRDAD MEMARIAN, ALI JAVADI, and ROOHOLLAH FATEH, “ANTIFUNGAL EFFECTS OF GOLD NANOPARTICLES CONJUGATED FLUCONAZOLE AGAINST FLUCONAZOLE RESISTANT STRAINS OF CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH CHRONIC VULVOVAGINITIS,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 10, no. 7, pp. 10–19, 2016, [Online]. Available: https://sid.ir/paper/132246/en

Related Journal Papers