Fabrication of Porous Biologic Hydroxyapatite Scaffold Reinforced with Polymer Coating for Bone Tissue Engineering Candidate

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

K. Sabree Israa; Abd Aladel Jabar Batool

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MATERIALS SCIENCE AND ENGINEERING Year:2023 | Volume:20 | Issue:3 Page(s): 1-10

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Fabrication of Porous Biologic Hydroxyapatite Scaffold Reinforced with Polymer Coating for Bone Tissue Engineering Candidate

Author(s)

K. Sabree Israa | Abd Aladel Jabar Batool | Issue Writer Certificate

Keywords

biologic hydroxyapatite

gel-casting

egg yolk

Polyvinyl alcohol

3D porous scaffold.

Abstract

Abstract. Hydroxyapatite (HA) scaffold is commonly used in the applications of bone tissue engineering due to its bioactivity and equivalent chemical composition to the inorganic constituents of human bone. The present study focused on the fabrication of porous 3D hydroxyapatite scaffold which was modified by polymer coating as a successful strategy to improve the mechanical properties. A 3D porous hydroxyapatite scaffolds were fabricated by gel-casting method by using freshly extracted egg yolk (EY) with (50 and 60)wt% of HA powder. To enhance the mechanical properties, composite PVA/ HA scaffolds were produced by using dip coating in Polyvinyl alcohol (PVA). Fourier transform infrared spectroscopy (FTIR) was used to recognize the functional group associated with the hydroxyapatite scaffolds before and after PVA coating. The physical (density and porosity) and mechanical (compressive strength and elastic modulus) properties were investigated before and after coating. SEM was used to inspect the surface morphology and pore modification of the scaffolds. Wettability was determined by using a water contact angle to analyze the scaffold hydrophobicity. Surface roughness was studied by atomic force microscopy (AFM). It was revealed that the scaffold porosity decreased with increase solid loading of HA powder in the gel and after PVA coating. The findings showed that PVA coating improved mechanical strength of scaffold to be double by covering the small pores and filling microcracks sited on the scaffold strut surfaces, inducing a crack bridging mechanism. The scaffolds’ strength was in the range of trabecular bone strength. This indicates non-load bearing applications.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans