BIOCHEMICAL EFFECTS OF FRUCTOSE DIET ON OBESITY IN ADULT MALE NMRI MICE

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POUYAMANESH Z.; YAGHMAEI P.; EBRAHIM HABIBI A.; MOHAMMAD AMOLI M.

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Journal: Journal of Food Technology and Nutrition Year:2016 | Volume:13 | Issue:1 (49) Page(s): 47-54

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Title

BIOCHEMICAL EFFECTS OF FRUCTOSE DIET ON OBESITY IN ADULT MALE NMRI MICE

Author(s)

POUYAMANESH Z. | YAGHMAEI P. | EBRAHIM HABIBI A. | MOHAMMAD AMOLI M. | Issue Writer Certificate

Keywords

FRUCTOSEQ2

FAT DIETQ2

MALE NMRI MICEQ2

OBESITYQ2

Abstract

Introduction: excessive use of artificial sweeteners along with increased body mass raises the risk of cardiovascular diseases, asthma, arthritis, type2 diabetes, stroke, high blood pressure and other diseases and leaves adverse metabolic effects. This study investigates the effect of FRUCTOSE on OBESITY and its effects on biochemical parameters in adult male mice (NMRI).Materials and Methods: Investigation was carried out in two stages. In the first stage of the treatment which lasted 8 weeks (n=6) the control group received water and rodent food; the obese group had a high-fat diet and the experimental group1received high-fat diet (1382 Kcal) along with 20% of FRUCTOSE gavage. In the second stage of the treatment which lasted 12weeks, the control group 2, obese group 2 (received rodent food for the last four weeks) and experimental group 2 (received FRUCTOSE with the same dosage for the last4 weeks) and the study continued for 12 week. The weights were measured every week and the amount of serum FRUCTOSE and biochemical parameters was measured by sandwich Elisa method.Results: Obese and the experimental group1showed more weight gain as compared to the control 1 and statistically the results were significant (P£0.001) but experimental 1 showed less weight as compared to the obese 1 but was not significant. Also the experimental group 2 showed higher weight gain as compared to control 2 which was statistically significant (P£0.001). FRUCTOSE levels were higher in all the groups as compared to the control group. The same result was observed for glucose, total cholesterol, TG, LDL with the decrease of HDL.Conclusion: The extra calorie intake is stored in the form of fat leading to weight gain and it is indicated that the receiving of 20% FRUCTOSE does not play a strong role in gaining weight.

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APA: Copy

POUYAMANESH, Z., YAGHMAEI, P., EBRAHIM HABIBI, A., & MOHAMMAD AMOLI, M.. (2016). BIOCHEMICAL EFFECTS OF FRUCTOSE DIET ON OBESITY IN ADULT MALE NMRI MICE. JOURNAL OF FOOD TECHNOLOGY AND NUTRITION, 13(1 (49)), 47-54. SID. https://sid.ir/paper/143377/en

Vancouver: Copy

POUYAMANESH Z., YAGHMAEI P., EBRAHIM HABIBI A., MOHAMMAD AMOLI M.. BIOCHEMICAL EFFECTS OF FRUCTOSE DIET ON OBESITY IN ADULT MALE NMRI MICE. JOURNAL OF FOOD TECHNOLOGY AND NUTRITION[Internet]. 2016;13(1 (49)):47-54. Available from: https://sid.ir/paper/143377/en

IEEE: Copy

Z. POUYAMANESH, P. YAGHMAEI, A. EBRAHIM HABIBI, and M. MOHAMMAD AMOLI, “BIOCHEMICAL EFFECTS OF FRUCTOSE DIET ON OBESITY IN ADULT MALE NMRI MICE,” JOURNAL OF FOOD TECHNOLOGY AND NUTRITION, vol. 13, no. 1 (49), pp. 47–54, 2016, [Online]. Available: https://sid.ir/paper/143377/en

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