CONJUGATED LINOLEIC ACID LOADED NANOSTRUCTURED LIPID CARRIERS (NLC): OPTIMIZATION OF PARTICLE SIZE BY RESPONSE SURFACE METHODOLOGY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FARID AGHAEE S.; GHANBARZADEH B.; HAMISHEKAR H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF FOOD RESEARCH (UNIVERSITY OF TABRIZ) Year:2015 | Volume:25 | Issue:3 Page(s): 441-456

Download Full-Text

Persian Verion

View:

1,368

Download:

Cites:

Information Journal Paper

Title

CONJUGATED LINOLEIC ACID LOADED NANOSTRUCTURED LIPID CARRIERS (NLC): OPTIMIZATION OF PARTICLE SIZE BY RESPONSE SURFACE METHODOLOGY

Author(s)

FARID AGHAEE S. | GHANBARZADEH B. | HAMISHEKAR H. | Issue Writer Certificate

Keywords

PARTICLE SIZE

CONJUGATED LINOLEIC ACID

NANOSTRUCTURED LIPID CARRIERS

Abstract

Conjugated linoleic acid (CLA) is a type of nutraceuticals which can be used in functional food development however, it is sensitive to oxidation. NANOSTRUCTURED LIPID CARRIERS (NLC) were used for the encapsulation of CONJUGATED LINOLEIC ACID by hot homogenization method. Among four different solid lipids used in the production of this system (precirol ATO-5, Compritol ATO-888, Cacao butter and lauric acid) only precirol was able to produce acceptable PARTICLE SIZE and structure. On the next step, on the basis of response surface method and central composite design, various concentrations of precirol and aqueous phase surfactant (poloxamer) and different ratios of liquid to solid lipid (conjugated linoleic acid to precirol) were used to find the optimum sample of CLA bearing NLC. The PARTICLE SIZE and PARTICLE SIZE distribution (Span) were in the range of 75-2040 nanometer and 0.44-5.16, respectively and it was observed that by increasing the concentrations of solid lipid and aqueous phase surfactant, the PARTICLE SIZE increased considerably. Also, increment in liquid to solid lipid ratio enhanced PARTICLE SIZE stability. The NLC formulation containing 2% (w/v) surfactant, 2% (w/v) precirol solid lipid and 50% of CLA to solid lipid ratio was chosen as optimum sample by 93 nm PARTICLE SIZE and was stable at 4˚C during 45 days of preservation.

Cites

No record.

References

No record.

Cite

APA: Copy

FARID AGHAEE, S., GHANBARZADEH, B., & HAMISHEKAR, H.. (2015). CONJUGATED LINOLEIC ACID LOADED NANOSTRUCTURED LIPID CARRIERS (NLC): OPTIMIZATION OF PARTICLE SIZE BY RESPONSE SURFACE METHODOLOGY. JOURNAL OF FOOD RESEARCH (UNIVERSITY OF TABRIZ), 25(3), 441-456. SID. https://sid.ir/paper/148537/en

Vancouver: Copy

FARID AGHAEE S., GHANBARZADEH B., HAMISHEKAR H.. CONJUGATED LINOLEIC ACID LOADED NANOSTRUCTURED LIPID CARRIERS (NLC): OPTIMIZATION OF PARTICLE SIZE BY RESPONSE SURFACE METHODOLOGY. JOURNAL OF FOOD RESEARCH (UNIVERSITY OF TABRIZ)[Internet]. 2015;25(3):441-456. Available from: https://sid.ir/paper/148537/en

IEEE: Copy

S. FARID AGHAEE, B. GHANBARZADEH, and H. HAMISHEKAR, “CONJUGATED LINOLEIC ACID LOADED NANOSTRUCTURED LIPID CARRIERS (NLC): OPTIMIZATION OF PARTICLE SIZE BY RESPONSE SURFACE METHODOLOGY,” JOURNAL OF FOOD RESEARCH (UNIVERSITY OF TABRIZ), vol. 25, no. 3, pp. 441–456, 2015, [Online]. Available: https://sid.ir/paper/148537/en

Related Journal Papers