FIELD EVALUATION OF TWO KILLED BIVALENT VACCINES NEWCASTLE AND GUMBORO DISEASES IN COMMERCIAL LAYER CHICKENS

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HAGHIGHI KHOSHKHOO P.; HOSSEINI H.; AKBARI AZAD G.; MASOUMIAN S.

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Journal: JOURNAL OF VETERINARY MICROBIOLOGY Year:2010 | Volume:6 | Issue:1 (19) Page(s): 63-67

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Title

FIELD EVALUATION OF TWO KILLED BIVALENT VACCINES NEWCASTLE AND GUMBORO DISEASES IN COMMERCIAL LAYER CHICKENS

Author(s)

HAGHIGHI KHOSHKHOO P. | HOSSEINI H. | AKBARI AZAD G. | MASOUMIAN S. | Issue Writer Certificate

Keywords

KILLED VACCINEQ3

HUMORAL IMMUNITYQ2

ELISAQ2

NEWCASTLE DISEASEQ2

GUMBORO DISEASEQ3

Abstract

This field trial was done to evaluate the efficacy of two killed bivalent vaccines to create the antibody titer against ND and IBD. Forty six thousand one-day-old Hy-line (W36) pullet chicks were randomly divided into two groups. Group 1 as a test group (with population of 16000 pullets) and Group 2 as a control group (with population of 30000 pullets) received vaccine A and B respectively at 8 days of age via subcutaneous rout injection. Another vaccine programs, diet and rearing situations were almost the same for two groups. At 5, 36, 50 and 64 days of age, 20 blood samples were taken from each group and antibody titers were assessed by ELISA and HH methods against IBD and ND respectively. Statistic analysis of data by t-test method showed that antibody mean titer and coefficient of variation (CV) against ND and IBD were not different among groups 1 and 2 significantly (p>0.05). In spite of high titers of AB against IBD, group 1 (control) showed IBD diseases with high mortality rate and typical clinical signs at 5th and 6th weeks of rearing period. It seems that in some diseases such as IBD which cell mediated immunity (CMI) is very important, evaluation of vaccines based on serological tests is not reliable and CMI must be evaluated too.

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APA: Copy

HAGHIGHI KHOSHKHOO, P., HOSSEINI, H., AKBARI AZAD, G., & MASOUMIAN, S.. (2010). FIELD EVALUATION OF TWO KILLED BIVALENT VACCINES NEWCASTLE AND GUMBORO DISEASES IN COMMERCIAL LAYER CHICKENS. JOURNAL OF VETERINARY MICROBIOLOGY, 6(1 (19)), 63-67. SID. https://sid.ir/paper/152027/en

Vancouver: Copy

HAGHIGHI KHOSHKHOO P., HOSSEINI H., AKBARI AZAD G., MASOUMIAN S.. FIELD EVALUATION OF TWO KILLED BIVALENT VACCINES NEWCASTLE AND GUMBORO DISEASES IN COMMERCIAL LAYER CHICKENS. JOURNAL OF VETERINARY MICROBIOLOGY[Internet]. 2010;6(1 (19)):63-67. Available from: https://sid.ir/paper/152027/en

IEEE: Copy

P. HAGHIGHI KHOSHKHOO, H. HOSSEINI, G. AKBARI AZAD, and S. MASOUMIAN, “FIELD EVALUATION OF TWO KILLED BIVALENT VACCINES NEWCASTLE AND GUMBORO DISEASES IN COMMERCIAL LAYER CHICKENS,” JOURNAL OF VETERINARY MICROBIOLOGY, vol. 6, no. 1 (19), pp. 63–67, 2010, [Online]. Available: https://sid.ir/paper/152027/en

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