THE CLINICAL INVESTIGATION OF SECURIGERA SECURIDACA (L.) (DEGEN & DOERFLER) SEEDS IN TYPE II DIABETIC PATIENTS; A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FALAH HOSSEINI H.; HOSSEINI P.; RAHMANI M.; ARDESHIR LARIJANI MOHAMMAD BAGHER; YAZDANI D.; HEMATI MOQADAM H.R.; HESHMAT RAMIN; ALAVI S.H.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medicinal Plants Year:2006 | Volume:5 | Issue:20 Page(s): 75-79

Download Full-Text

Persian Verion

View:

43,198

Download:

Cites:

Information Journal Paper

Title

THE CLINICAL INVESTIGATION OF SECURIGERA SECURIDACA (L.) (DEGEN & DOERFLER) SEEDS IN TYPE II DIABETIC PATIENTS; A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY

Author(s)

Keywords

SECURIGERA SECURIDACAQ4

HERBAL MEDICINEQ3

DIABETESQ3

CLINICAL STUDYQ2

Abstract

Backgrounds and Aims: SECURIGERA SECURIDACA (L.) seeds are used by traditional herbalists for the treatment of DIABETES in several parts of Iran. Clinical investigation of its efficacy and its toxicity in diabetic patients is of importance.Methods: A 2-month randomized double blind clinical trial was conducted in 70 type II diabetic patients in two well – matched groups. One group (n=35) received 500 mg SECURIGERA SECURIDACA (L.) seeds capsule 3 times a day plus standard therapy, while the control group (n=35) received placebo plus standard therapy. The patients were visited monthly and glycosylated hemoglobin (HbA1c), fasting blood glucose, total cholesterol, LDL and HDL, triglyceride, SGOT, SGPT, ALK, BUN, serum creatinine levels were determined at the beginning and the end of the study after two months.Results: There was no significant change in HbA1c and fasting blood glucose level in SECURIGERA SECURIDACA (L.) seeds treated patients after two months as compared to beginning of the treatment and also as compare to placebo group. Serum lipid level also did not change significantly. The liver enzyme level and creatinine level in blood did not change significantly in SECURIGERA SECURIDACA (L.) seeds treated patients. No side effect was observed in any of patients in both of the groups.Conclusion: The results show that the SECURIGERA SECURIDACA (L.) seeds treatment with known antidiabetic property in traditional herbal therapy has no beneficial effect on improving glycemic profile in type II diabetic patients. The use of this HERBAL MEDICINE in the dose of 1500mg in 3 divided dose showed no gasterointestinal symptom as well as liver and kidney abnormality during two months therapy. The long term efficacy and toxicity of this HERBAL MEDICINE in higher dosage may be investigated in large multi center CLINICAL STUDY.

Cites

No record.

References

Cite

APA: Copy

FALAH HOSSEINI, H., HOSSEINI, P., RAHMANI, M., ARDESHIR LARIJANI, MOHAMMAD BAGHER, YAZDANI, D., HEMATI MOQADAM, H.R., HESHMAT, RAMIN, & ALAVI, S.H.R.. (2006). THE CLINICAL INVESTIGATION OF SECURIGERA SECURIDACA (L.) (DEGEN & DOERFLER) SEEDS IN TYPE II DIABETIC PATIENTS; A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY. JOURNAL OF MEDICINAL PLANTS, 5(20), 75-79. SID. https://sid.ir/paper/15246/en

Vancouver: Copy

FALAH HOSSEINI H., HOSSEINI P., RAHMANI M., ARDESHIR LARIJANI MOHAMMAD BAGHER, YAZDANI D., HEMATI MOQADAM H.R., HESHMAT RAMIN, ALAVI S.H.R.. THE CLINICAL INVESTIGATION OF SECURIGERA SECURIDACA (L.) (DEGEN & DOERFLER) SEEDS IN TYPE II DIABETIC PATIENTS; A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY. JOURNAL OF MEDICINAL PLANTS[Internet]. 2006;5(20):75-79. Available from: https://sid.ir/paper/15246/en

IEEE: Copy

H. FALAH HOSSEINI, P. HOSSEINI, M. RAHMANI, MOHAMMAD BAGHER ARDESHIR LARIJANI, D. YAZDANI, H.R. HEMATI MOQADAM, RAMIN HESHMAT, and S.H.R. ALAVI, “THE CLINICAL INVESTIGATION OF SECURIGERA SECURIDACA (L.) (DEGEN & DOERFLER) SEEDS IN TYPE II DIABETIC PATIENTS; A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY,” JOURNAL OF MEDICINAL PLANTS, vol. 5, no. 20, pp. 75–79, 2006, [Online]. Available: https://sid.ir/paper/15246/en

Related Journal Papers