EFFECT OF PAPAVERINE ON HUMAN SERUM ALBUMIN GLYCATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AHMADZADEH A.; SHAHRIARI ALI REZA; GHAFARZADEGAN R.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medicinal Plants Year:2012 | Volume:11 | Issue:42 Page(s): 53-61

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

811

Download:

Cites:

Information Journal Paper

Title

EFFECT OF PAPAVERINE ON HUMAN SERUM ALBUMIN GLYCATION

Author(s)

AHMADZADEH A. | SHAHRIARI ALI REZA | GHAFARZADEGAN R. | Issue Writer Certificate

Keywords

GLYCATIONQ2

HUMAN SERUM ALBUMINQ2

PAPAVERINEQ2

Abstract

Background: GLYCATION is a non enzymatic reaction initiated by the primary addition of sugar to the amino groups of proteins.In the early stage of glyction, the synthesis of intermediates leading to formation of Amadori compounds occurs. In the late stage, advanced GLYCATION end product (AGE) are irreversibly formed after a Complex cascade of reaction.Objective: Survey effect of PAPAVERINE on HUMAN SERUM ALBUMIN GLYCATION.Methods: In this study HSA incubate with Glucose and different PAPAVERINE concentration for 42 days at 37oC. also HSA incubate alone (control sample), with Glucose (glycated sample) and with different PAPAVERINE concentration (without Glucose) respectively under the same conditions. Then samples survey with circular dichroism fluorescence and UV spectroscopy.Results: HSA GLYCATION increase in proportion to PAPAVERINE concentration. samples contain Glucose and PAPAVERINE show more change in secondary structure, free amino groups and AGE fluorescence in relation to glycated and control samples.Conclusion: In glycatedα helix and b sheet show 5.7% decrease and 3.1% increase in comparison to control respectively. Glycated show 14.2% fluorescence more than control. Free lys number in glycated show 8% less than control sample. All this cases show more change in samples which contain PAPAVERINE and Glucose. Seem PAPAVERINE change HSA and cause more lys contact with sugar thus PAPAVERINE increase GLYCATION.

Cites

No record.

References

No record.

Cite

APA: Copy

AHMADZADEH, A., SHAHRIARI, ALI REZA, & GHAFARZADEGAN, R.. (2012). EFFECT OF PAPAVERINE ON HUMAN SERUM ALBUMIN GLYCATION. JOURNAL OF MEDICINAL PLANTS, 11(42), 53-61. SID. https://sid.ir/paper/15306/en

Vancouver: Copy

AHMADZADEH A., SHAHRIARI ALI REZA, GHAFARZADEGAN R.. EFFECT OF PAPAVERINE ON HUMAN SERUM ALBUMIN GLYCATION. JOURNAL OF MEDICINAL PLANTS[Internet]. 2012;11(42):53-61. Available from: https://sid.ir/paper/15306/en

IEEE: Copy

A. AHMADZADEH, ALI REZA SHAHRIARI, and R. GHAFARZADEGAN, “EFFECT OF PAPAVERINE ON HUMAN SERUM ALBUMIN GLYCATION,” JOURNAL OF MEDICINAL PLANTS, vol. 11, no. 42, pp. 53–61, 2012, [Online]. Available: https://sid.ir/paper/15306/en

Related Journal Papers