REVIEW OF ANTIVIRAL EFFECTS OF GLYCYRRHIZA GLABRA L. AND ITS ACTIVE COMPONENT, GLYCYRRHIZIN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NASIRIASL M.; HOSSEINZADEH H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medicinal Plants Year:2007 | Volume:6 | Issue:22 Page(s): 1-12

Download Full-Text

Persian Verion

View:

4,821

Download:

Cites:

Information Journal Paper

Title

REVIEW OF ANTIVIRAL EFFECTS OF GLYCYRRHIZA GLABRA L. AND ITS ACTIVE COMPONENT, GLYCYRRHIZIN

Author(s)

NASIRIASL M. | HOSSEINZADEH H. | Issue Writer Certificate

Keywords

LICORICEQ2

GLYCYRRHIZIC ACIDQ2

HCVQ3

CMVQ3

ANTIVIRALQ3

Abstract

Background: LICORICE (Glycyrrhiza sp.) belongs to family of Leguminosae. A number of components have been isolated from LICORICE, including triterpene saponins, flavonoids, isoflavonoides, chalcones and various other substances. GLYCYRRHIZIC ACID is the main biologically active component of it. Objective: The aim of this review is to provide an updated overview of experimental investigations focused on the antivirus effects of Glycyrrhiza and its active component, glycyrrhizin.Methods: A computerized search of published articles was performed using the electronic database such as MEDLINE from 1980 to 2005. Results: Glycyrrhiza exerts ANTIVIRAL activity toward a number of viruses, including hepatitis A, B, C, varicella zoster, HIV, herpes simplex type-1, SARS, cytomegalo virus. Now GLYCYRRHIZIC ACID has been used for the treatment of the patients with chronic active hepatitis and about the mechanism of glycyrrhizin’s activity against other viruses, it seems that glycyrrhizin inhibits replication, affects cellular signaling pathways, upregulate expression of inducible nitrous oxide synthase and production of nitrous oxide in macrophages. Conclusion: Thus, it seems that future clinical research is needed to define the possible use of LICORICE and it active component, GLYCYRRHIZIC ACID as effective antivirus agents for treatment other viral infections.

Cites