EFFECT OF ALLIUM SATIVUM L. EXTRACT ON ACID AND PEPSIN SECRETION IN BASAL CONDITION AND STIMULATED WITH VAG STIMULATE IN RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHAHRANI M.; RAFIEIAN MAHMOUD; SHIRZAD H.A.; HASHEMZADEH CHALESHTORI M.; YOUSEFI H.; KHADIVI R.; AMINI S.A.; DEHGHAN M.; KHEYRI S.; MORADI M.; RAHIMIAN G.; GHIASI I.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medicinal Plants Year:2007 | Volume:6 | Issue:24 Page(s): 28-37

Download Full-Text

Persian Verion

View:

1,189

Download:

Cites:

Information Journal Paper

Title

EFFECT OF ALLIUM SATIVUM L. EXTRACT ON ACID AND PEPSIN SECRETION IN BASAL CONDITION AND STIMULATED WITH VAG STIMULATE IN RAT

Author(s)

Keywords

ALLIUM SATIVUM EXTRACTQ3

GASTRIC ACIDQ3

GASTRIC PEPSIN - GARLIC EXTRACTQ3

VAGUS STIMULATEQ3

Abstract

Background: Garlic is used world wide to give flavor to foods as pecols ect. by different nations specially by Iranian society. The dominant believe is, the garlic therapeutic effects on patients with gastric discomfort and digesting problems. Objective: in this study we aimed to investigate the garlic effect on GASTRIC ACID and pepsin in both basic and stimulated condition by electrical stimulus of vogues nerve in rat. Methods: in an experimental study two groups of 12 wistar rats were selected. to make the animal unconscious, 50mg/kg Sodium Tiopantal were given ip. and each rat was tracheostomized, laparatomized, gastrodeodonostomized and then 100mg/kg of garlic extract dissolved in 9%saline was introduced to stomach of animal. The vagus nerves of both side of the neck released from carotid sheet and stimulated with 15millivolts, frequency 4 Herts and 1 milisecond wide. The stomach secretions then washed out in following stages; first base, second base, VAGUS STIMULATEd conditions and reverse to base. The acid amounts of washing were measured by titrometry and pepsin amounts were measured with Anson technique. Results: the acid and pepsin secretion were significantly increased in rats received garlic extracts (p<0.000 p<0.05 respectively). Stimulation by vagus nerves in control group significantly increased the level of acid (p<0.05) and pepsin (p<0.05) and garlic treated group had similar secretion rate to stimulated group. Furthermore there were no significant relationship between sex of studied rats.Conclusion: consumption of garlic in the diet has lots of benefits for digestion of foods, so it can be beneficial for those patients with digestive problems, however it should be noted that people with digestive dysfunction related to increased level of GASTRIC ACID or pepsin must avoid garlic consumption. Therefore patient with gastritis and duodenal ulcer are not allowed to take garlic in their diet.

Cites

No record.

References

Cite

APA: Copy

SHAHRANI, M., RAFIEIAN, MAHMOUD, SHIRZAD, H.A., HASHEMZADEH CHALESHTORI, M., YOUSEFI, H., KHADIVI, R., AMINI, S.A., DEHGHAN, M., KHEYRI, S., MORADI, M., RAHIMIAN, G., & GHIASI, I.. (2007). EFFECT OF ALLIUM SATIVUM L. EXTRACT ON ACID AND PEPSIN SECRETION IN BASAL CONDITION AND STIMULATED WITH VAG STIMULATE IN RAT. JOURNAL OF MEDICINAL PLANTS, 6(24), 28-37. SID. https://sid.ir/paper/15630/en

Vancouver: Copy

SHAHRANI M., RAFIEIAN MAHMOUD, SHIRZAD H.A., HASHEMZADEH CHALESHTORI M., YOUSEFI H., KHADIVI R., AMINI S.A., DEHGHAN M., KHEYRI S., MORADI M., RAHIMIAN G., GHIASI I.. EFFECT OF ALLIUM SATIVUM L. EXTRACT ON ACID AND PEPSIN SECRETION IN BASAL CONDITION AND STIMULATED WITH VAG STIMULATE IN RAT. JOURNAL OF MEDICINAL PLANTS[Internet]. 2007;6(24):28-37. Available from: https://sid.ir/paper/15630/en

IEEE: Copy

M. SHAHRANI, MAHMOUD RAFIEIAN, H.A. SHIRZAD, M. HASHEMZADEH CHALESHTORI, H. YOUSEFI, R. KHADIVI, S.A. AMINI, M. DEHGHAN, S. KHEYRI, M. MORADI, G. RAHIMIAN, and I. GHIASI, “EFFECT OF ALLIUM SATIVUM L. EXTRACT ON ACID AND PEPSIN SECRETION IN BASAL CONDITION AND STIMULATED WITH VAG STIMULATE IN RAT,” JOURNAL OF MEDICINAL PLANTS, vol. 6, no. 24, pp. 28–37, 2007, [Online]. Available: https://sid.ir/paper/15630/en

Related Journal Papers