EVALUATION OF ANALGESIC EFFECT OF SESAME OIL AND LECITHIN DIETS IN HOT PLATE AND FORMALIN TEST ON AGED MALE RATS

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MOHAMMADPOUR KARGAR H.; SHAFAHI M.; KESMATI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Medicinal Plants Year:2012 | Volume:11 | Issue:SUPPLEMENT 9 Page(s): 216-224

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Title

EVALUATION OF ANALGESIC EFFECT OF SESAME OIL AND LECITHIN DIETS IN HOT PLATE AND FORMALIN TEST ON AGED MALE RATS

Author(s)

MOHAMMADPOUR KARGAR H. | SHAFAHI M. | KESMATI M. | Issue Writer Certificate

Keywords

SESAME OILQ2

UNSATURATED FATTYQ2

LECITHINQ2

PAINQ3

HOT PLATEQ2

FORMALIN TESTQ2

Abstract

Background: SESAME OIL is applied in physiological research as a solvent. It contains UNSATURATED FATTY acids such as linoleic acid, sesamol and LECITHIN. In his research effect of dietary SESAME OIL on PAIN perception was studied.Objective:Methods: N-MRI male rats (360±20 g) were used. Animals divided to two groups: 1) control group and 2) experimental group (three subgroups that ate dietary plats that contain 10% SESAME OIL for 28, 42 and 56 days respectively and a subgroup ate dietary plats that contain 1% LECITHIN). After 28, 42 and 56 days PAIN was evaluateded by digital HOT PLATE and FORMALIN TEST. Data was analyzed by one way ANOVA or T- test.Results: HOT PLATE test: SESAME OIL diet decreased PAIN in the 28, 42, 56 days significantly.Formalin test: SESAME OIL diet decreased PAIN only in 42 days (p<0.02) significantly in early phase. SESAME OIL diet decreased PAIN in the 28 days (p<0.0001) and 42 days (p<0.03) and 56 days (p<0.001) significantly in late phase of FORMALIN TEST and also we found significant difference between control and LECITHIN group (p<0.006) in late phase.Hot plate test: Dietary plats (10% SESAME OIL) decreased acute PAIN perception in all experimental groups (p<0.03).Conclusion: Our data indicated that dietary SESAME OIL could increase PAIN threshold. It seems that SESAME OIL LECITHIN (as a source for acetylcholine) or UNSATURATED FATTY acid (altered plasma membrane properties or PGs metabolism) involve in this PAIN threshold alternation.

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APA: Copy

MOHAMMADPOUR KARGAR, H., SHAFAHI, M., & KESMATI, M.. (2012). EVALUATION OF ANALGESIC EFFECT OF SESAME OIL AND LECITHIN DIETS IN HOT PLATE AND FORMALIN TEST ON AGED MALE RATS. JOURNAL OF MEDICINAL PLANTS, 11(SUPPLEMENT 9), 216-224. SID. https://sid.ir/paper/15750/en

Vancouver: Copy

MOHAMMADPOUR KARGAR H., SHAFAHI M., KESMATI M.. EVALUATION OF ANALGESIC EFFECT OF SESAME OIL AND LECITHIN DIETS IN HOT PLATE AND FORMALIN TEST ON AGED MALE RATS. JOURNAL OF MEDICINAL PLANTS[Internet]. 2012;11(SUPPLEMENT 9):216-224. Available from: https://sid.ir/paper/15750/en

IEEE: Copy

H. MOHAMMADPOUR KARGAR, M. SHAFAHI, and M. KESMATI, “EVALUATION OF ANALGESIC EFFECT OF SESAME OIL AND LECITHIN DIETS IN HOT PLATE AND FORMALIN TEST ON AGED MALE RATS,” JOURNAL OF MEDICINAL PLANTS, vol. 11, no. SUPPLEMENT 9, pp. 216–224, 2012, [Online]. Available: https://sid.ir/paper/15750/en

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