EVALUATION OF SAFETY OF MINOXIDIL 5%+ CHAMOMILE 7% TOPICAL SOLUTION

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SAMADI ANISEH; AHMAD NASROLLAHI SAMAN; FIROOZ ALIREZA

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Paper Information

Journal: Dermatology and Cosmetics Year:2015 | Volume:6 | Issue:4 Page(s): 183-189

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Title

EVALUATION OF SAFETY OF MINOXIDIL 5%+ CHAMOMILE 7% TOPICAL SOLUTION

Author(s)

SAMADI ANISEH | AHMAD NASROLLAHI SAMAN | FIROOZ ALIREZA | Issue Writer Certificate

Keywords

ANDROGENETIC ALOPECIAQ3

MINOXIDILQ2

CHAMOMILEQ2

SAFETYQ2

ADVERSE EFFECTSQ2

Abstract

Background and Aim: ANDROGENETIC ALOPECIA (AGA) is the most common form of alopecia in men, worldwide and topical MINOXIDIL appears to be the most effective and safe treatment for AGA beside oral finasteride. SAFETY assessment of topical MINOXIDIL formulation could be conducted using in vivo studies on human volunteers. Using skin biophysical parameters is a fast and noninvasive method for SAFETY assessment of topical products.Methods: A topical combination of MINOXIDIL 5% solution in combination with CHAMOMILE extract from Iran’s pharmaceutical market tested on the skin of the forearm of 15 healthy volunteers. Changes in trans epidermal water loss (TEWL), stratum corneum hydration, pH, melanin and hemoglobin contents have been evaluated, using biometric assessments with MPA 580 CutometerÒ.Results: There was not any significant change in skin hydration (P=0.692), TEWL (P=0.191), stratum corneum pH (P=0.613), melanin (P=0.533), and hemoglobin (P=0.579) contents before and after topical MINOXIDIL application.Conclusion: No significant change detected in skin erythema and assessed parameters Application of MINOXIDIL 5%+ CHAMOMILE 7% topical solution on human volunteers has not shown any ADVERSE EFFECTS and these formulations could be recommended to use.

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APA: Copy

SAMADI, ANISEH, AHMAD NASROLLAHI, SAMAN, & FIROOZ, ALIREZA. (2015). EVALUATION OF SAFETY OF MINOXIDIL 5%+ CHAMOMILE 7% TOPICAL SOLUTION. DERMATOLOGY AND COSMETIC, 6(4), 183-189. SID. https://sid.ir/paper/157592/en

Vancouver: Copy

SAMADI ANISEH, AHMAD NASROLLAHI SAMAN, FIROOZ ALIREZA. EVALUATION OF SAFETY OF MINOXIDIL 5%+ CHAMOMILE 7% TOPICAL SOLUTION. DERMATOLOGY AND COSMETIC[Internet]. 2015;6(4):183-189. Available from: https://sid.ir/paper/157592/en

IEEE: Copy

ANISEH SAMADI, SAMAN AHMAD NASROLLAHI, and ALIREZA FIROOZ, “EVALUATION OF SAFETY OF MINOXIDIL 5%+ CHAMOMILE 7% TOPICAL SOLUTION,” DERMATOLOGY AND COSMETIC, vol. 6, no. 4, pp. 183–189, 2015, [Online]. Available: https://sid.ir/paper/157592/en

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