DESMIN EXPRESSION BY A GASTROINTESTINAL STROMAL TUMOR IN A DOG

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HESARAKI S.; NASSIRI S.M.; AZIZI SARAJI A.

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Journal: Iranian Journal of Veterinary Medicine Year:2010 | Volume:4 | Issue:4 Page(s): 245-247

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Information Journal Paper

Title

DESMIN EXPRESSION BY A GASTROINTESTINAL STROMAL TUMOR IN A DOG

Author(s)

HESARAKI S. | NASSIRI S.M. | AZIZI SARAJI A. | Issue Writer Certificate

Keywords

DOGQ2

GASTROINTESTINAL STROMAL TUMORQ3

C-KITQ3

DESMINQ3

Abstract

This report describes the histological and immunohistochemical features of a small intestinal tumor that resembled a human GASTROINTESTINAL STROMAL TUMOR (GISTs) in a seven-year-old male cross-breed DOG. This was unique because of the expression of DESMIN by the tumor. Grossly, the white-gray tumor measured 8.0´4.0´6.5 cm and was 760 gram in weight. It was cystic and enveloped the jejunum. 100 and C-KIT and negative for CD34 on immunohistochemistry. The expression of DESMIN in the cytoplasmof this tumor cells is a rare event in these types of tumors. Histopathologically, long spindleshaped cells were arranged densely in the interwoven pattern. The tumor cells had a low rate of mitosis, were pleomorphic, and were positive for vimentin, a-smooth muscle actin, DESMIN, S100 and C-KIT and negative for CD34 on immunohistochemistry. The expression of DESMIN in the cytoplasm of this tumor vells is a rare event in these types of tumors.

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APA: Copy

HESARAKI, S., NASSIRI, S.M., & AZIZI SARAJI, A.. (2010). DESMIN EXPRESSION BY A GASTROINTESTINAL STROMAL TUMOR IN A DOG. IRANIAN JOURNAL OF VETERINARY MEDICINE (INTERNATIONAL JOURNAL OF VETERINARY RESEARCH), 4(4), 245-247. SID. https://sid.ir/paper/157968/en

Vancouver: Copy

HESARAKI S., NASSIRI S.M., AZIZI SARAJI A.. DESMIN EXPRESSION BY A GASTROINTESTINAL STROMAL TUMOR IN A DOG. IRANIAN JOURNAL OF VETERINARY MEDICINE (INTERNATIONAL JOURNAL OF VETERINARY RESEARCH)[Internet]. 2010;4(4):245-247. Available from: https://sid.ir/paper/157968/en

IEEE: Copy

S. HESARAKI, S.M. NASSIRI, and A. AZIZI SARAJI, “DESMIN EXPRESSION BY A GASTROINTESTINAL STROMAL TUMOR IN A DOG,” IRANIAN JOURNAL OF VETERINARY MEDICINE (INTERNATIONAL JOURNAL OF VETERINARY RESEARCH), vol. 4, no. 4, pp. 245–247, 2010, [Online]. Available: https://sid.ir/paper/157968/en

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