POPULATION DATA ON D6S2879 AND D6S2806 MARKERS LOCATED AT HLA-DRB1 REGION IN THE IRANIANS: IDENTIFYING THE SIGNATURES OF BALANCING AND DIRECTIONAL SELECTION

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TAJADOD MANSOUREH; VALLIAN BOROUJENI SADEQ; FAZELI ATTAR ZAHRA

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Journal: JOURNAL OF TAXONOMY AND BIOSISTEMATICS Year:2011 | Volume:3 | Issue:8 Page(s): 45-53

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Title

POPULATION DATA ON D6S2879 AND D6S2806 MARKERS LOCATED AT HLA-DRB1 REGION IN THE IRANIANS: IDENTIFYING THE SIGNATURES OF BALANCING AND DIRECTIONAL SELECTION

Author(s)

TAJADOD MANSOUREH | VALLIAN BOROUJENI SADEQ | FAZELI ATTAR ZAHRA | Issue Writer Certificate

Keywords

HLA-DRB1 GENEQ4

GENE DIVERSITYQ4

EWENS-WATTERSON TESTQ4

MHC MICROSATELLITE MARKERQ4

SELECTIONQ4

Abstract

In this study, the genetic diversity and neutrality test for the MHC microsatellite loci, D6S2879 and D6S2806, located within the HLA-DRB1 GENE region, were investigated. The genotyping data from 73 unrelated individuals were analyzed for Shannon index, the effective allele number of the markers and neutrality test by use of PyPop and Popgene32 programs. The Shannon index for D6S2879 and D6S2806 markers in the studied population was 1.0372 and 0.8601, respectively. The Fnd value computed for D6S2879 and D6S2806 markers were also estimated -0.8449 and 0.9904, respectively. The results obtained from EWENS-WATTERSON TEST indicated that D6S2879 and D6S2806 markers were under balancing and directional SELECTION in the Iranian populations, respectively. The data suggested the presence of a SELECTION force on HLA-DRB1 GENE region in the Iranian populations.

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APA: Copy

TAJADOD, MANSOUREH, VALLIAN BOROUJENI, SADEQ, & FAZELI ATTAR, ZAHRA. (2011). POPULATION DATA ON D6S2879 AND D6S2806 MARKERS LOCATED AT HLA-DRB1 REGION IN THE IRANIANS: IDENTIFYING THE SIGNATURES OF BALANCING AND DIRECTIONAL SELECTION. JOURNAL OF TAXONOMY AND BIOSISTEMATICS, 3(8), 45-53. SID. https://sid.ir/paper/160192/en

Vancouver: Copy

TAJADOD MANSOUREH, VALLIAN BOROUJENI SADEQ, FAZELI ATTAR ZAHRA. POPULATION DATA ON D6S2879 AND D6S2806 MARKERS LOCATED AT HLA-DRB1 REGION IN THE IRANIANS: IDENTIFYING THE SIGNATURES OF BALANCING AND DIRECTIONAL SELECTION. JOURNAL OF TAXONOMY AND BIOSISTEMATICS[Internet]. 2011;3(8):45-53. Available from: https://sid.ir/paper/160192/en

IEEE: Copy

MANSOUREH TAJADOD, SADEQ VALLIAN BOROUJENI, and ZAHRA FAZELI ATTAR, “POPULATION DATA ON D6S2879 AND D6S2806 MARKERS LOCATED AT HLA-DRB1 REGION IN THE IRANIANS: IDENTIFYING THE SIGNATURES OF BALANCING AND DIRECTIONAL SELECTION,” JOURNAL OF TAXONOMY AND BIOSISTEMATICS, vol. 3, no. 8, pp. 45–53, 2011, [Online]. Available: https://sid.ir/paper/160192/en

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