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Information Journal Paper

Title

EFFECT OF HUMAN SPERM CHROMATIN ANOMALIES ON FERTILIZATION OUTCOME POST ICSI

Pages

  43-49

Abstract

 Introduction: The aim of this study was to evaluate the effect of SPERM CHROMATIN anomalies on fertilization outcome post ICSI.Material and Methods: Therefore along with semen parameters, CMA3 staining for PROTAMINE DEFICIENCY, aniline blue staining for excessive histones, SDS for SPERM CHROMATIN stability and SDS+EDTA for ability of sperm to undergo decondensation were carried out on 55 semen samples from patients referring for ICSI to Isfahan fertility and infertility cente.Result: The results showed that among the aforementioned tests and semen parameters, only CMA3 showed a significant correlation with fertilization outcome post ICSI. Patients were also grouped according to CMA3 level of <30% or >30 % or fertilization rate of <50%, or >50%. The results showed that the mean percentage fertilization and mean percentage of CMA3 positivity is different inboth groups respectively. The area under ROC curve showed that CMA3 is a highly sensitive and specific test for prediction of fertilization outcome post ICSI.Conclusion: Therefore, it can be concluded that sperm PROTAMINE DEFICIENCY has profound effect on fertilization failure in ICSI.

Cites

References

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APA: Copy

NASRESFAHANI, MOHAMMAD HOSSEIN, RAZAVI, SH., MARDANI, M., MAFI, A., & MOGHADAM, A.. (2004). EFFECT OF HUMAN SPERM CHROMATIN ANOMALIES ON FERTILIZATION OUTCOME POST ICSI . CELL JOURNAL (YAKHTEH), 6(21), 43-49. SID. https://sid.ir/paper/16439/en

Vancouver: Copy

NASRESFAHANI MOHAMMAD HOSSEIN, RAZAVI SH., MARDANI M., MAFI A., MOGHADAM A.. EFFECT OF HUMAN SPERM CHROMATIN ANOMALIES ON FERTILIZATION OUTCOME POST ICSI . CELL JOURNAL (YAKHTEH)[Internet]. 2004;6(21):43-49. Available from: https://sid.ir/paper/16439/en

IEEE: Copy

MOHAMMAD HOSSEIN NASRESFAHANI, SH. RAZAVI, M. MARDANI, A. MAFI, and A. MOGHADAM, “EFFECT OF HUMAN SPERM CHROMATIN ANOMALIES ON FERTILIZATION OUTCOME POST ICSI ,” CELL JOURNAL (YAKHTEH), vol. 6, no. 21, pp. 43–49, 2004, [Online]. Available: https://sid.ir/paper/16439/en

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