MENTAL HEALTH CONCEPTS IN POST HUMAN GENOME ERA

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SHAHSAVAND ANANLOO E.

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Journal Paper

Paper Information

Journal: Iranian Journal of Psychiatry and Clinical Psychology Year:2010 | Volume:16 | Issue:3 (62) Page(s): 365-365

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Information Journal Paper

Title

MENTAL HEALTH CONCEPTS IN POST HUMAN GENOME ERA

Author(s)

SHAHSAVAND ANANLOO E. | Issue Writer Certificate

Keywords

HUMAN GENOMEQ4

PREVENTIONQ4

TREATMENTQ4

Abstract

In psychiatry, the sophistication of behavioural phenotypes is a major obstacle. Current models of schizophrenia, for example, depend on basic phenotypes such as gating deficits or endophenotypes. As understanding of neurobiology improves, the methods described will merge and susceptibility genes will be identified. Confirming their role will require interpretation of expression (Transcriptome) and protein products (Proteome). The Future: Research in neuroscience is improving our molecular understanding of neurodevelopment and brain function. New epidemiological approaches (e.g., Genomic Epidemiology) will also be required to examine for and interpret interactions between genetic and environmental risk factors in people. Gene identification may be only the first step, but it begins a process that will expose the genetic architecture and biology of psychiatric disorders. Animal models will be needed to study the behavioural impact of genes in vivo in specific systems and through neurodevelopment. Requirements for storage, analysis and interpretation of the vast amount of biological data generated by the HUMAN GENOME Project and other projects (e.g., transcriptome, proteome, metabolome …) have spawned a new science, bioinformatics. As the draft genome is completed, integrated databases of gene structure, transcripts and proteomics are being developed which will contribute to our understanding of gene functions and their relationships to mental disorders. Post-genomic research may forever change how we classify and treat mental disorders. Genetic insights into behaviour may fundamentally alter how we view the individual and his or her responsibilities. But for common disorders and traits, susceptibility genes will only be risk factors and we must never forget the importance of environmental influences.

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APA: Copy

SHAHSAVAND ANANLOO, E.. (2010). MENTAL HEALTH CONCEPTS IN POST HUMAN GENOME ERA. IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, 16(3 (62)), 365-365. SID. https://sid.ir/paper/17001/en

Vancouver: Copy

SHAHSAVAND ANANLOO E.. MENTAL HEALTH CONCEPTS IN POST HUMAN GENOME ERA. IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY[Internet]. 2010;16(3 (62)):365-365. Available from: https://sid.ir/paper/17001/en

IEEE: Copy

E. SHAHSAVAND ANANLOO, “MENTAL HEALTH CONCEPTS IN POST HUMAN GENOME ERA,” IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, vol. 16, no. 3 (62), pp. 365–365, 2010, [Online]. Available: https://sid.ir/paper/17001/en

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