STUDY ON THE ANTIDIABETIC EFFECT OF CARBON TETRACHLORIDE EXTRACT OF TRIGONELLA FOENUM SEED IN STREPTOZOCIN INDUCED DIABETIC RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZAHEDIASL S.; ZARE B.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Avicenna Journal of Clinical Medicine Year:2005 | Volume:12 | Issue:3 (SN 37) Page(s): 10-15

Download Full-Text

Persian Verion

View:

835

Download:

Cites:

Information Journal Paper

Title

STUDY ON THE ANTIDIABETIC EFFECT OF CARBON TETRACHLORIDE EXTRACT OF TRIGONELLA FOENUM SEED IN STREPTOZOCIN INDUCED DIABETIC RATS

Author(s)

ZAHEDIASL S. | ZARE B. | Issue Writer Certificate

Keywords

CARBON TETRACHLORIDEQ3

DIABETES MELLITUSQ3

RATSQ3

STREPTOZOCIN TRIGONELLA FOENUMQ3

Abstract

Introduction & Objective: DIABETES MELLITUSisa disease with a long history. Attempts to relieve the symptoms have not been totally successful. The seeds of Trigonella foenum have been shown to possess hypoglycemic properties. In this study hypoglycemic effect of the carbon tetra chloride (CCL4) extract of these seeds has been investigated.Materials & Methods: Using Wistar RATS, diabetes was induced by intravenous injections of 100 mg/kg of STZ in three doses divided over three consecutive days. The extract was prepared by the maceration method and administered orally in different doses. Blood samples were collected and serum glucose was measured by the O-toloidin method.Results: The results indicated that the extract can reduce serum glucose in a dose depend'ent manner (r=0.44, P=0.00) and the maximum effect occurred with a dose of 4g/kg. With this dose, serum glucose concentration was reduced from 547±44 to 345±35 mg/dl P=0.0000001). Conclusion: The results of this study indicated that the CCL4 extract of trigonella foenum seeds have anti-diabetic effect, when it is introduced orally. The purification and formulation of its effective substance (s) for therapeutic purposes deserves consideration.

Cites

References

No record.

Cite

APA: Copy

ZAHEDIASL, S., & ZARE, B.. (2005). STUDY ON THE ANTIDIABETIC EFFECT OF CARBON TETRACHLORIDE EXTRACT OF TRIGONELLA FOENUM SEED IN STREPTOZOCIN INDUCED DIABETIC RATS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 12(3 (SN 37)), 10-15. SID. https://sid.ir/paper/17288/en

Vancouver: Copy

ZAHEDIASL S., ZARE B.. STUDY ON THE ANTIDIABETIC EFFECT OF CARBON TETRACHLORIDE EXTRACT OF TRIGONELLA FOENUM SEED IN STREPTOZOCIN INDUCED DIABETIC RATS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2005;12(3 (SN 37)):10-15. Available from: https://sid.ir/paper/17288/en

IEEE: Copy

S. ZAHEDIASL, and B. ZARE, “STUDY ON THE ANTIDIABETIC EFFECT OF CARBON TETRACHLORIDE EXTRACT OF TRIGONELLA FOENUM SEED IN STREPTOZOCIN INDUCED DIABETIC RATS,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 12, no. 3 (SN 37), pp. 10–15, 2005, [Online]. Available: https://sid.ir/paper/17288/en

Related Journal Papers