COMPARATIVE STUDY OF THRAPEUTIC EFFCTS OF%20 AZELAIC ACID AND %4 HYDROQUINONE CREAM IN TREATMENT OF MELASMA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BAHADORI MOJGAN; ESHGHI GHOLAMREZA; KHEZRIAN LEILA; SEIFRABIEI MOHAMMAD ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Avicenna Journal of Clinical Medicine Year:2017 | Volume:23 | Issue:4 (SN 82) Page(s): 300-305

Download Full-Text

Persian Verion

View:

2,582

Download:

Cites:

Information Journal Paper

Title

COMPARATIVE STUDY OF THRAPEUTIC EFFCTS OF%20 AZELAIC ACID AND %4 HYDROQUINONE CREAM IN TREATMENT OF MELASMA

Author(s)

BAHADORI MOJGAN | ESHGHI GHOLAMREZA | KHEZRIAN LEILA | SEIFRABIEI MOHAMMAD ALI | Issue Writer Certificate

Keywords

AZELAIC ACIDQ1

HYDROQUINONEQ1

MELASMAQ1

Abstract

Introduction: MELASMA is a recurrent ,symmetric ,and chronic acquired hyperpimentation that presents gray- brown macules and patches with determined margins in areas exposed to light. There are many treatment options with different efficacies and side effects. In this study the therapeutic effect of 20% AZELAIC ACID and 4% HYDROQUINONE in treatment of MELASMA was assessed.Methods: In this clinical trial ,the study population consisted of all patients with clinical diagnosis of MELASMA ,who referred to the outpatient clinic of dermatology of Hamadan ,Farshchian Hospital from December 2013 to July 2014. A total of 44 patients were recruited. Patients were randomly divided to two groups and each group was treated with either AZELAIC ACID or HYDROQUINONE for four months. The MASI score was used to evaluate the improvement. P values of≤0.05 were considered significant.Results: Of 44 patients,21 received 4% HYDROQUINONE and 23 received 20% AZELAIC ACID, with random allocation. Both groups were similar with respect to gender and age ,and there were no significant differences between the two groups. The MASI score in both groups had a decreasing trend over time ,and at the end of the fourth month ,a significant difference was found between the two groups (P=0.006). The overall mean MASI score in both groups had a significant difference at different times and during the entire trial period ,mean MASI score of 20% AZELAIC ACID was lower than 4% HYDROQUINONE (P=0.001).Conclusion: Based on this study ,we could conclude that 20% AZELAIC ACID in comparison with 4% HYDROQUINONE had better effects on treatment of MELASMA. Therefore ,20% AZELAIC ACID is a good alternative for 4% HYDROQUINONE in treatment of MELASMA.

Cites

No record.

References

No record.

Cite

APA: Copy

BAHADORI, MOJGAN, ESHGHI, GHOLAMREZA, KHEZRIAN, LEILA, & SEIFRABIEI, MOHAMMAD ALI. (2017). COMPARATIVE STUDY OF THRAPEUTIC EFFCTS OF%20 AZELAIC ACID AND %4 HYDROQUINONE CREAM IN TREATMENT OF MELASMA. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 23(4 (SN 82)), 300-305. SID. https://sid.ir/paper/17401/en

Vancouver: Copy

BAHADORI MOJGAN, ESHGHI GHOLAMREZA, KHEZRIAN LEILA, SEIFRABIEI MOHAMMAD ALI. COMPARATIVE STUDY OF THRAPEUTIC EFFCTS OF%20 AZELAIC ACID AND %4 HYDROQUINONE CREAM IN TREATMENT OF MELASMA. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2017;23(4 (SN 82)):300-305. Available from: https://sid.ir/paper/17401/en

IEEE: Copy

MOJGAN BAHADORI, GHOLAMREZA ESHGHI, LEILA KHEZRIAN, and MOHAMMAD ALI SEIFRABIEI, “COMPARATIVE STUDY OF THRAPEUTIC EFFCTS OF%20 AZELAIC ACID AND %4 HYDROQUINONE CREAM IN TREATMENT OF MELASMA,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 23, no. 4 (SN 82), pp. 300–305, 2017, [Online]. Available: https://sid.ir/paper/17401/en

Related Journal Papers