A COMPARATIVE INVESTIGATION OF NEUROPSYCHOLOGICAL DYSFUNCTIONS OF ANTIEPILEPTIC DRUGS IN EPILEPTIC PATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MAZDEH M.; ZAREI H.; ASGARI MOBARAKEH K.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Avicenna Journal of Clinical Medicine Year:2014 | Volume:21 | Issue:2 (SN 72) Page(s): 137-144

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,229

Download:

Cites:

Information Journal Paper

Title

A COMPARATIVE INVESTIGATION OF NEUROPSYCHOLOGICAL DYSFUNCTIONS OF ANTIEPILEPTIC DRUGS IN EPILEPTIC PATIENTS

Author(s)

MAZDEH M. | ZAREI H. | ASGARI MOBARAKEH K. | Issue Writer Certificate

Keywords

ANTICONVULSANTSQ2

BEHAVIORAL DISORDERSQ2

COGNITION DISORDERSQ2

EPILEPSYQ2

Abstract

Introduction & Objective: Patients suffering from EPILEPSY can experience a wide range of neuropsychological disorders such as impaired memory, attention and information processing. The aim of the present study was to evaluate and compare the performance of neuropsychological epileptic patients according to their pharmacotherapy.Materials & Methods: In this retrospective causal- comparative study, 90 patients with idiopathic grand mal EPILEPSY in three groups of 30 subjects taking drug valproate acid, carbamazepine and combination lamotrigine (with carbamazepine or valproate) were selected in Hamadan clinics in 2012.30 cases of normal subjects with an age range of 15 to 55 years were included (control group). The four groups of subjects were matched in age and education and were evaluated according to continuous performance tests, Benton visual retention test, and Paced Auditory Serial Addition Test (PASAT). The data was analyzed by SPSS software and Manova, Scheffe, Tamhane tests.Results: The results show that the rate of PASAT in normal group was significantly higher than EPILEPSY group (P=0.01), but among the groups taking valproate acid, carbamazepine and combination lamotrigine (with carbamazepine or valproate) no significant difference was observed in the level of depression. In PASAT and Benton visual retention tests the results were similar. In continuous performance test n the scale of incorrect response the results were reversed and with regard to the correct response, the previous results were confirmed.On omission reply scale, the group which used combination lamotrigine and the normal group showed similar results, thus they were separated from the group using carbamazepine and valproate. On reaction time scale, patients taking carbamazepine significantly (P=0.01) differed from patients taking amotrigine and valproate and from the normal group.Conclusion: There are significant differences between the AEDs as valporate, carbamazepine and combination therapy in terms of their neuropsychological profiles.

Cites

AN OVERVIEW OF PSYCHOLOGICAL FACTORS IN EPILEPSY

References

No record.

Cite

APA: Copy

MAZDEH, M., ZAREI, H., & ASGARI MOBARAKEH, K.. (2014). A COMPARATIVE INVESTIGATION OF NEUROPSYCHOLOGICAL DYSFUNCTIONS OF ANTIEPILEPTIC DRUGS IN EPILEPTIC PATIENTS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 21(2 (SN 72)), 137-144. SID. https://sid.ir/paper/17522/en

Vancouver: Copy

MAZDEH M., ZAREI H., ASGARI MOBARAKEH K.. A COMPARATIVE INVESTIGATION OF NEUROPSYCHOLOGICAL DYSFUNCTIONS OF ANTIEPILEPTIC DRUGS IN EPILEPTIC PATIENTS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2014;21(2 (SN 72)):137-144. Available from: https://sid.ir/paper/17522/en

IEEE: Copy

M. MAZDEH, H. ZAREI, and K. ASGARI MOBARAKEH, “A COMPARATIVE INVESTIGATION OF NEUROPSYCHOLOGICAL DYSFUNCTIONS OF ANTIEPILEPTIC DRUGS IN EPILEPTIC PATIENTS,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 21, no. 2 (SN 72), pp. 137–144, 2014, [Online]. Available: https://sid.ir/paper/17522/en

Related Journal Papers