THE EFFECT OF HYPOTHYROIDISM ON MORPHINE DEPENDENCE IN MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MIRAZI N.; HASANEIN P.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE) Year:2007 | Volume:1 | Issue:3 Page(s): 31-37

Download Full-Text

Persian Verion

View:

837

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF HYPOTHYROIDISM ON MORPHINE DEPENDENCE IN MICE

Author(s)

MIRAZI N. | HASANEIN P. | Issue Writer Certificate

Keywords

HYPOTHYROIDISMQ3

DEPENDENCEQ3

MORPHINEQ3

WITHDRAWAL SIGNSQ3

Abstract

In this study, physical DEPENDENCE in male hypothyroid Swiss-Webster mice was investigated by evaluating of MORPHINE WITHDRAWAL SIGNS. Animals were divided into four groups: control, MORPHINE dependent, hypothyroid and hypothyroid MORPHINE dependent. HYPOTHYROIDISM was induced by administering propylthioracil (PTU) 0.1% for 2 weeks into drinking water of the animals. Animals at control groups only received tap water. MORPHINE dependency was induced by intraperituneal injection of MORPHINE hydrochloride for 4 days according to Marschall method. WITHDRAWAL SIGNS were evaluated 1 hour after the last administration of MORPHINE by intraperituneal injection of naloxone in experimental groups. The results of the present study showed that MORPHINE DEPENDENCE was greater in hypothyroid animals compared to control and dependent groups and WITHDRAWAL SIGNS were more serious (P<0.05). These results suggest that HYPOTHYROIDISM could affect on MORPHINE DEPENDENCE by possible altering in numbers or affinities of the opioid receptors in the nervous system.

Cites

No record.

References

No record.

Cite

APA: Copy

MIRAZI, N., & HASANEIN, P.. (2007). THE EFFECT OF HYPOTHYROIDISM ON MORPHINE DEPENDENCE IN MICE. JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE), 1(3), 31-37. SID. https://sid.ir/paper/175482/en

Vancouver: Copy

MIRAZI N., HASANEIN P.. THE EFFECT OF HYPOTHYROIDISM ON MORPHINE DEPENDENCE IN MICE. JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE)[Internet]. 2007;1(3):31-37. Available from: https://sid.ir/paper/175482/en

IEEE: Copy

N. MIRAZI, and P. HASANEIN, “THE EFFECT OF HYPOTHYROIDISM ON MORPHINE DEPENDENCE IN MICE,” JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE), vol. 1, no. 3, pp. 31–37, 2007, [Online]. Available: https://sid.ir/paper/175482/en

Related Journal Papers