NEPHROTOXIC EFFECTS OF NANOSILVER IN BROILER CHICKENS

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AKRADI L.; AMIRI ANDI M.; SALIMI NAGHANI E.; AHMADI F.

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Journal: JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE) Year:2011 | Volume:5 | Issue:2 Page(s): 25-31

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Title

NEPHROTOXIC EFFECTS OF NANOSILVER IN BROILER CHICKENS

Author(s)

AKRADI L. | AMIRI ANDI M. | SALIMI NAGHANI E. | AHMADI F. | Issue Writer Certificate

Keywords

SILVERQ2

KIDNEYQ2

BROILERSQ2

URIC ACIDQ2

HISTOPATHOLOGYQ2

Abstract

Nanoparticle of SILVER, with creating free radicals, can destroy many bacteria, viruses and fungi; therefore they have been recommended as a disinfectant in livestock’s production system. In this study 240 Ross 308 strain chicks in a completely randomized design (CRD) in four treatments at 0(control), 4, 8 and 12 ppm levels of SILVER nanoparticles in drinking water with four replicates within 16 separate floor pens and 15 birds in each pen were reared. At the end of growing period from each pen two BROILERS with the average weight were selected and after taking blood sample, sacrificed and their KIDNEY were examined with light microscope by H&E staining. HISTOPATHOLOGY showed dose depended changes such as congestion, presence of inflammatory cells including heterophile and lymphocytes, necrosis in tubular cells, proliferative glomerulonephritis and fibrosis. Lesions in the treatments 3 (8ppm) and 4 (12ppm) were more sever than the group 2 (4ppm). Also, increased serum uricacid in treatment 4 (12ppm) compared to control group was significant (p<0.05). It can be concluded that using of nanoSILVER higher than 8ppm in drinking water can induce sever lesions in KIDNEY of chickens.

Cites

THE EFFECT OF SILVER NANOPARTICLES COATED ON CLINOPTILOLITE ON PERFORMANCE, LIVER ENZYMES AND BLOOD LIPID CONCENTRATIONS OF BROILER CHICKENS

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APA: Copy

AKRADI, L., AMIRI ANDI, M., SALIMI NAGHANI, E., & AHMADI, F.. (2011). NEPHROTOXIC EFFECTS OF NANOSILVER IN BROILER CHICKENS. JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE), 5(2), 25-31. SID. https://sid.ir/paper/175594/en

Vancouver: Copy

AKRADI L., AMIRI ANDI M., SALIMI NAGHANI E., AHMADI F.. NEPHROTOXIC EFFECTS OF NANOSILVER IN BROILER CHICKENS. JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE)[Internet]. 2011;5(2):25-31. Available from: https://sid.ir/paper/175594/en

IEEE: Copy

L. AKRADI, M. AMIRI ANDI, E. SALIMI NAGHANI, and F. AHMADI, “NEPHROTOXIC EFFECTS OF NANOSILVER IN BROILER CHICKENS,” JOURNAL OF LARGE ANIMAL CLINICAL SCIENCE RESEARCH (JOURNAL OF VETERINARY MEDICINE), vol. 5, no. 2, pp. 25–31, 2011, [Online]. Available: https://sid.ir/paper/175594/en

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