EFFECT OF ALKALINE PHOSPHATASE ON THE ENZYMES AND PROTEINS OF LIVER TISSUE OF RAT BY ENZYME INHIBITION

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SAMANI JAHROMI E.; ZOLGHADRI JAHROMI S.

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Journal: JOURNAL OF ANIMAL BIOLOGY Year:2015 | Volume:7 | Issue:4 Page(s): 11-17

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Title

EFFECT OF ALKALINE PHOSPHATASE ON THE ENZYMES AND PROTEINS OF LIVER TISSUE OF RAT BY ENZYME INHIBITION

Author(s)

SAMANI JAHROMI E. | ZOLGHADRI JAHROMI S. | Issue Writer Certificate

Keywords

ALKALINE PHOSPHATASEQ2

LIVERQ2

ENZYME INHIBITIONQ2

L- HOMO ARGININQ2

Abstract

Liver is the largest gland in the body; which have different secretions. ALKALINE PHOSPHATASE enzyme is one of them. The aim of this study is the investigation of ALKALINE PHOSPHATASE effect on the enzymes and proteins of LIVER in the male rats on the basis of ENZYME INHIBITION by LHomo argenine. In this experimental study, 35 adult male rats were studied. They were randomly divided into 5 groups with seven rats in each group, including: control, sham and testing 1, 2 and 3 respectively. Control group were nourished by food and water; Sham group were injected just solvent. Group 1: 0.2 mg/ml ALKALINE PHOSPHATASE enzyme was injected. In Group 2: 2 mg/ml Lhomo arginine inhibitors were injected. Group 3: First 2 mg/ml L-homo arginine was injected, then after 2 hours, 0.2 mg/ml ALKALINE PHOSPHATASE injection was done. All injections continued for 5 days. At the end of duration, a sample was prepared for evaluating ALP. Data was collected by using SPSS software and by one-way variance analytical tests (ANOVA) in significance P<0.05. The activities of aspartate amino transferase (AST) and ALKALINE PHOSPHATASE (ALP) has increased significantly in experimental group 1 compared to the control (at P<0.05). However, there was no significant change in the alanine aminotransferase (ALT) activity and the concentrations of total protein and albumin in these groups. Injection of ALKALINE PHOSPHATASE cause to increasing the activity of ALKALINE PHOSPHATASE and aspartate aminotransferase, as well as causing damage to LIVER tissue. The use of L-Homo arginine inhibitor prevents damage to the LIVER cells.

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APA: Copy

SAMANI JAHROMI, E., & ZOLGHADRI JAHROMI, S.. (2015). EFFECT OF ALKALINE PHOSPHATASE ON THE ENZYMES AND PROTEINS OF LIVER TISSUE OF RAT BY ENZYME INHIBITION. JOURNAL OF ANIMAL BIOLOGY, 7(4), 11-17. SID. https://sid.ir/paper/176811/en

Vancouver: Copy

SAMANI JAHROMI E., ZOLGHADRI JAHROMI S.. EFFECT OF ALKALINE PHOSPHATASE ON THE ENZYMES AND PROTEINS OF LIVER TISSUE OF RAT BY ENZYME INHIBITION. JOURNAL OF ANIMAL BIOLOGY[Internet]. 2015;7(4):11-17. Available from: https://sid.ir/paper/176811/en

IEEE: Copy

E. SAMANI JAHROMI, and S. ZOLGHADRI JAHROMI, “EFFECT OF ALKALINE PHOSPHATASE ON THE ENZYMES AND PROTEINS OF LIVER TISSUE OF RAT BY ENZYME INHIBITION,” JOURNAL OF ANIMAL BIOLOGY, vol. 7, no. 4, pp. 11–17, 2015, [Online]. Available: https://sid.ir/paper/176811/en

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