AN EVALUATION OF THE EFFECTIVENESS OF PYRIDOXINE IN THE TREATMENT OF NAUSEA AND VOMITING DURING PREGNANCY

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NIROUMANESH SHIRIN; REZAEI Z.; ASHKEVARI P.

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Journal: Researcher Bulletin of Medical Sciences Year:2000 | Volume:5 | Issue:2 (18) Page(s): 173-178

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Title

AN EVALUATION OF THE EFFECTIVENESS OF PYRIDOXINE IN THE TREATMENT OF NAUSEA AND VOMITING DURING PREGNANCY

Author(s)

NIROUMANESH SHIRIN | REZAEI Z. | ASHKEVARI P. | Issue Writer Certificate

Keywords

PREGNANCY-ASSOCIATED NAUSEA AND VOMITINGQ4

PYRIDOXINEQ4

RANDOMIZED TRIALQ4

Abstract

This randomized, double blind, placebo-controlled trial was performed on 200 pregnant women at a gestation age less than 17 weeks to evaluate the effectiveness of PYRIDOXINE in PREGNANCY-ASSOCIATED NAUSEA AND VOMITING. In this respect, 100 of them received PYRIDOXINE tablets (20 mg) three times a day for 5 consecutive days and the remainder (control group) (n=100) received placebo with the same order. The average values for age, age of pregnancy, and other background variables showed no statistically significant difference between the two groups. For collection of data, the patients were taught to record the severity of their nausea by visual analogue scale and the number of vomiting episodes and the quality of their appetite over 24 hours before treatment and again during 5 consecutive days of treatment in especially-designed forms. After treatment, the mean score of severity of nausea was significantly less in PYRIDOXINE-treated group compared to placebo group (P<0.05). In addition, the mean number of vomiting episodes was also less in PYRIDOXINE group, but did m\not reach to a significant level and there was an improvement in the quality of appetite from the 2nd to 5th day and the difference was significant (P<0.03).

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APA: Copy

NIROUMANESH, SHIRIN, REZAEI, Z., & ASHKEVARI, P.. (2000). AN EVALUATION OF THE EFFECTIVENESS OF PYRIDOXINE IN THE TREATMENT OF NAUSEA AND VOMITING DURING PREGNANCY. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 5(2 (18)), 173-178. SID. https://sid.ir/paper/18233/en

Vancouver: Copy

NIROUMANESH SHIRIN, REZAEI Z., ASHKEVARI P.. AN EVALUATION OF THE EFFECTIVENESS OF PYRIDOXINE IN THE TREATMENT OF NAUSEA AND VOMITING DURING PREGNANCY. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2000;5(2 (18)):173-178. Available from: https://sid.ir/paper/18233/en

IEEE: Copy

SHIRIN NIROUMANESH, Z. REZAEI, and P. ASHKEVARI, “AN EVALUATION OF THE EFFECTIVENESS OF PYRIDOXINE IN THE TREATMENT OF NAUSEA AND VOMITING DURING PREGNANCY,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 5, no. 2 (18), pp. 173–178, 2000, [Online]. Available: https://sid.ir/paper/18233/en

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